Sökning: "CAR-receptor regulation"

Hittade 1 avhandling innehållade orden CAR-receptor regulation.

1. 1. Expression of Genes Encoding for Drug Metabolism in the Small Intestine

   Författare :Monica Lindell; Hans Lennernäs; Matti Lang; Olavi Pelkonen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; CYPs; UGTs; interindividual variation; small intestine; human; rat; artemisinin; CAR-receptor regulation; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

   Sammanfattning : This investigation focused on the mRNA expression of drug metabolising Cytochromes P-450 (CYP) and UDP-glucuronosyltransferases (UGT) and the transport protein P-glycoprotein (Pgp) in the small intestine of humans and rats.The mRNA expression of the investigated genes in the human small intestine (duodenum) varies between individuals giving each one of us personal profile. LÄS MER