Sökning: "CA IX"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden CA IX.

1. 6. Pharmacokinetic dosing of factor VIII and factor IX in prophylactic treatment of haemophilia

   Författare :Maj Carlsson; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; Prophylaxis; Pharmacokinetics; Pharmaceutical service; Haemophilia B; Haemophilia A; Factor IX; Factor VIII; Drug distribution; Cost-effectiveness; Dosage; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : The aim of the thesis was to increase cost-effectiveness in prophylactic treatment of haemophilia. Prophylaxis is effective to prevent bleedings and arthropathy, but the high cost limits its use. First, a new distribution system for clotting factor concentrates was implemented in Sweden to improve availability and reduce risks and costs. LÄS MER

3. 7. Pfennigmärkte und Währungslandschaften : Monetarisierungen im sächsisch-slawischen Grenzland ca. 965-1120

   Författare :Christoph Kilger; Bernd Kluge; Stockholms universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; arkeologi; Archaeology;

   Sammanfattning : How was money used in early medieval times and by whom? Why did people accept silver coins as a common means of payment? How can we understand the beginnings of a monetary economy? How can we describe and properly analyse the physical remains of monetary thinking like the numerous coin finds and silver hoards from this period? To address these questions the author studies the relationship between monetary systems operating in the Saxon-Slavic borderlands and corresponding coin finds from the early medieval period, between c. 965 and 1120. LÄS MER

4. 8. HEMOPHILIA A AND B WITH SPECIAL REFERENCE TO INHIBITOR DEVELOPMENT AND EXPERIMENTAL STUDIES OF FACTORS VIII AND IX

   Författare :Karin Knobe; Enheten för pediatrisk hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; inhibitors; mutations; Factor IX; Factor VIII; coagulation; hemophilia A and B; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : The general objective of the research underlying this dissertation was to conduct clinical and basic scientific studies to further elucidate the hemophilia and the coagulation process, with the goal of improving the care of families with these disorders. More specific aims were to evaluate epidemiological, genetic, clinical, and biochemical aspects of the development of inhibitors (antibodies) against FVIII and FIX in Swedish patients with hemophilia A and B (papers I, II, and III). LÄS MER

5. 9. Cartilage Oligomeric Matrix Protein (COMP). Functions in collagen binding and assembly

   Författare :Krisztina Rosenberg; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; Klinisk biologi;

   Sammanfattning : Connective tissues contain a prominent extracellular matrix that provides mechanical and physical properties. This extracellular matrix contains as a major constituent a network of collagen fibres. These are composed of collagen fibrils, which in turn are assembled from many collagen molecules aligned parallel to each other. Several proteins, e. LÄS MER

7. 10. Crystallographic studies on porphyrin metallation by ferrochelatase

   Författare :David Lecerof; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; thermal and mechanical properties; Condensed matter:stucture; fasjämvikt; kristallografi; egenskaper termiska och mekaniska ; Kondenserade materiens egenskaper:struktur; crystallography; phase equilibria; Magnesium; pi-helix; Zinc; ferrochelatase; Metal binding; porphyrin metallation;

   Sammanfattning : Ferrochelatase catalyses the terminal step in heme biosynthesis by inserting a ferrous ion into protoporphyrin IX. The reaction mechanism has in this thesis been studied by mainly crystallographic methods. LÄS MER