Sökning: "C. trachomatis"

Visar resultat 11 - 15 av 34 avhandlingar innehållade orden C. trachomatis.

  1. 11. Towards novel antibacterials : Synthesis and identification of natural product inspired inhibitors of Chlamydia trachomatis and development of chemical probes targeting virulence of Pseudomonas aeruginosa

    Författare :Michael Saleeb; Mikael Elofsson; Anna Linusson Jonsson; Andreas Kirschning; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibacterials; antibiotics; small molecules; natural products; benzofuran; dihydrobenzofuran; the type III secretion system; Pseudomonas aeruginosa; Chlamydia trachomatis; phenotypic screening; high-throughput screening; surface plasmon resonance; drug discovery; bacterial toxins; enzyme inhibitors; organisk kemi; Organic Chemistry;

    Sammanfattning : Antibiotic resistance has evolved significantly to become one of the serious threats to public health today. Yet, the pipeline of new antibiotics is drying up and is lagging behind the challenging needs. LÄS MER

  3. 12. Improving the prevention of sexually transmitted infections (STIs) : a study using Chlamydia trachomatis as a model infection

    Författare :Daniel Novak; Roger Karlsson; Berit Andersen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; STI; Prevention; Chlamydia; Postal screening; cost effective; condom; Internet; self-selective screening; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Family Medicine; allmänmedicin;

    Sammanfattning : Despite the current preventive strategies sexually transmitted infections (STIs) are rising. This thesis presents a model with the aim of improving the prevention of STIs. Chlamydia being the most common STI in Sweden serves as a model infection. The presented model is based on five performed studies. LÄS MER

  4. 13. Plant-produced STI vaccine antigens with special emphasis on HIV-1 p24

    Författare :Ingrid Lindh; Åke Strid; Sören Andersson; Edward Rybicki; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant-based vaccines; Arabidopsis thaliana; HIV-1; p24; GALT; mucosal immunity; Chlamydia trachomatis; MOMP; Daucus carota; Chemistry; Kemi; Chemistry; Kemi;

    Sammanfattning : Objective: To establish stable transgenic non-toxic plants as a platform for plant-based vaccine production as well as potential oral delivery system of vaccine antigens for sexually transmitted infections (STIs). The concept is to immunize the mucosal immune system present in the gut-associated lymphoid tissues (GALT). LÄS MER

  5. 14. Identification and Characterization of Biomarkers in Bacterial Infections

    Författare :Martin Storm; Lars Engstrand; Ann-Christine Syvänen; Hans-Jurg Monstein; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Microbiology; Bacteriology; Chlamydia trachomatis; Bordetella perussis; Helicobacter pylori; Real-Time PCR; Microarray; Antigenome; Vaccine; Biomarker; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : In recent years molecular biology has become an integral part of the clinical laboratory. With an ever increasing number of methodologies and applications being presented each year it has increased our knowledge of how bacteria cause disease as well as our ability to predict disease outcome. LÄS MER

  7. 15. Urethritis and cervicitis with special reference to Chlamydia trachomatis and Mycoplasma genitalium : diagnostic and epidemiological aspects

    Författare :Lars Falk; Torvald Ripa; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The aim of this thesis was to elucidate urethritis and cervicitis and the possible causes with special reference to Chlamydia trachomatis and Mycoplasma genitalium. Despite mandatory partner notification legislated in 1988, the incidence of C trachomatis infection in Sweden has undergone a 10% annual increase since 1997, following a decline in the early 1990s. LÄS MER