Sökning: "C terminus"

Visar resultat 1 - 5 av 167 avhandlingar innehållade orden C terminus.

  1. 1. Reactivity and Selectivity Studies in Iridium-Catalyzed Asymmetric Hydrogenation

    Författare :Bram B. C. Peters; Pher G. Andersson; Xavier Verdaguer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Asymmetric hydrogenation; Chemoselectivity; Enantioconvergency; Iridium catalysis; Multi-reduction; Organic Chemistry; organisk kemi;

    Sammanfattning : Transition-metal catalyzed stereoselective hydrogenation constitutes an indispensable method for the preparation of chiral molecules. The work in this thesis describes the development of efficient catalytic asymmetric hydrogenations with a focus on the elucidation of reactivity patterns and chemoselectivity in hydrogenations. LÄS MER

  3. 2. Structure and function of the HDL receptor SR-BI : scavenger receptor class B type I

    Författare :Magnus S.C. Johnson; Göteborgs universitet; []
    Nyckelord :SR-BI; HDL; Cholesterol; Scavenger receptor; Apoptosis; Ovary; Gallbladder; Peroxisome;

    Sammanfattning : Low plasma levels of high-density lipoprotein (HDL) and high levels of low-density lipoprotein (LDL) are well-recognized risk factors for cardiovascular disease. The uptake and degradation of LDL cholesterol have been characterized in detail at the molecular level. Less is known about the metabolism and cellular uptake of HDL cholesterol. LÄS MER

  4. 3. The Francisella pathogenicity island : its role in type VI secretion and intracellular infection

    Författare :Lena Meyer; Anders Sjöstedt; Siobhan C. Cowley; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella; FPI; Type VI Secretion; Igl; DotU; VgrG; Pdp; microinjection; phagosomal escape; intracellular replication; Clinical Bacteriology; klinisk bakteriologi;

    Sammanfattning : Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. LÄS MER

  5. 4. A New Look into Protein C Inhibitor : Posttranslational Modifications and their Functions

    Författare :Wei Sun; Sophia Schedin Weiss; Hakon Leffler; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein C inhibitor; posttranslational modifications; N-glycan; O-glycan; mass spectrometry; factor Xa; thrombin; prostate specific antigen; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Sammanfattning : The influences of posttranslational modifications on the functions of the versatile serpin protein C inhibitor (PCI) were studied. PCI is a serine protease inhibitor that is expressed in many tissues and secreted to various fluids in human, including blood plasma, seminal plasma, and urine. LÄS MER

  7. 5. The Plant Plasma Memrbane H+-ATPase: regulation by phosphorylation and 14-3-3 proteins

    Författare :Anne Olsson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phosphorylation; fusicoccin; 14-3-3; C-terminus; autoinhibitory domain; plasma membrane; plant; H -ATPase; Plant biochemistry; Växtbiokemi;

    Sammanfattning : The plant plasma membrane H+-ATPase is a predominant membrane enzyme that provides the energy for secondary active transport across the plasma membrane. Consequently, the H+-ATPase is thought to play a major role in many cell processes, and it is implicated to be regulated by a number of factors, including hormones, blue light, and fungal toxins The plant plasma membrane H+-ATPase is regulated via an autoinhibitory domain located within the C-terminal region of the enzyme. LÄS MER