Sökning: "C EBP transcription factors"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden C EBP transcription factors.

  1. 1. Neuroinflammation in Alzheimer's disease : Focus on NF-κB and C/EBP transcription factors

    Författare :Veronica Ramberg; Kerstin Iverfeldt; Josep Saura; Stockholms universitet; []
    Nyckelord :Alzheimer’s disease; neuroinflammation; NF-κB; C EBP; apoptosis; caspases; FRET; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Alzheimer's disease (AD) is the most common form of dementia among elderly. The disease is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic neuroinflammation. LÄS MER

  3. 2. C/EBP transcription factors in lung cellular differentiation and development

    Författare :Tove Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :C EBP transcription factors; lung; development; differentiation; glucocorticoid regulation;

    Sammanfattning : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. LÄS MER

  4. 3. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells

    Författare :Malin Samuelsson; Kerstin Iverfeldt; Piet Eikelenboom; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-β; astrocytes; C EBP; glia; microglia; neuroinflammation; NF-кB; Neurochemistry; Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. LÄS MER

  5. 4. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression

    Författare :Per Antonson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Basic leucine zipper; CCAATEnhancer Binding Protein; CEBP; DNA binding protein; Gene expression; Transcription factor;

    Sammanfattning : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipper class of transcription factors with a total of 6 members having been identified in this family so far. This gene family has been mainly implicated in regulation of cell specific gene expression and differentiation. LÄS MER

  7. 5. Regulation of gene expression in pulmonary inflammation and differentiation : a role for C/EBP transcription factors

    Författare :Abraham B Roos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : CCAAT/enhancer-binding protein (C/EBP) transcription factors play essential roles in gene regulation. The lung-enriched isoform C/EBPα is known to inhibit proliferation, promote differentiation and stimulate gene expression characteristic of the mature differentiated pulmonary epithelium. LÄS MER