Sökning: "Burkitt Lymphoma"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden Burkitt Lymphoma.

  1. 1. Burkitt lymphoma and diffuse large B-cell lymphoma – therapeutic strategies and pathogenetic mechanisms

    Författare :Tove Wästerlid; Tumörmikromiljö; []
    Nyckelord :Burkitt Lymphoma; Chemotherapy; SOX11; Diffuse large B-cell lymphoma; Prognostic factors; Rituximab;

    Sammanfattning : Burkitt lymphoma (BL) is a rare, aggressive disorder constituting 1% of all non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) is more common, accounting for 30% of malignant lymphoma. Standard treatment for adult BL and for certain subgroups of patients with DLBCL remains to be defined due to paucity of randomised trials performed. LÄS MER

  3. 2. Protein kinases and phosphatases in B-cell lymphoma

    Författare :Marie Fridberg; Tumörmikromiljö; []
    Nyckelord :HePTP; PTEN; PKC-beta 2; B-cell; lymphoma; kinases; ZAP70; phosphatase; SHP2;

    Sammanfattning : Around 2000 persons are diagnosed with lymphoma in Sweden each year. There are many subgroups described for this form of cancer and the great majority is derived from B-cells. The most common subgroup is Diffuse large B-cell lymphoma (DLBCL), a highly aggressive disease where only half of the patients are cured. LÄS MER

  4. 3. Estrogens and lymphoma growth

    Författare :Muhammad Sharif Hasni; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lymphomas are generally not considered as endocrine-associated cancers. Nevertheless, most lymphoid malignancies show a gender differencein incidence and prognosis, with males being more affected.The molecular mechanism for this gender difference is unknown. LÄS MER

  5. 4. Apoptosis signaling in leukemia and lymphoma: understanding mechanisms of chemoresistance

    Författare :Astrid Ottosson Wadlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Apoptosis (programmed cell death) is a basic physiological process, essential in the balance between life and death of cells of normal tissues in the body. Apoptosis can be considered as cellular “suicide” initiated by the cell itself when infected by a virus or transformed into a cancer cell. LÄS MER

  7. 5. Assessment of therapeutic targets in experimental models of Myc-induced lymphoma

    Författare :Linus Plym Forshell; Jonas Nilsson; Lars-Gunnar Larsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Myc; Decitabine; Pim kinase; RCAS-tva; Neurobiology; Neurobiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Myc transcription factor activates expression of genes that promote cellular functions such as proliferation and cell growth. The deregulated Myc expression, characteristic for the tumor cell, also activates apoptosis, which selects for additional genetic changes deactivating the induced cell death. LÄS MER