Sökning: "Burkitt Iymphoma"

Hittade 2 avhandlingar innehållade orden Burkitt Iymphoma.

  1. 1. p53 inactivation by point mutations and splice site mutations in human and mouse tumors

    Författare :Kristinn P Magnússon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :p53; Burkitt Iymphoma; apoptosis; alternative splicing; mutation; ascites;

    Sammanfattning : The p53 tumor suppressor gene is frequently mutated in human tumors. p53 induces cell cycle arrest and/or apoptosis in response to cellular stress, such as DNA damage, hypoxia and certain activated oncogenes like c-myc. The status of p53 in Burkitt's Iymphoma (BL) cell lines was investigated. The majority of BL lines expressed mutated p53 protein. LÄS MER

  3. 2. Characteristics of EBV-infected B cell lines and B-CLL clones which determine their interaction with lymphocytes

    Författare :Javier Federico Avila-Carino; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :EBV; Burkitt Iymphoma; CLL; MLC; antiviral response phenotype; cytokines.;

    Sammanfattning : The results concerning T Iymphocyte mediated recognition of Epstein-Barr virus (EBV) carrying Burkitt Iymphoma (BL) cell lines and EBV-infected chronic Iymphocytic leukemia (CLL) B cells contribute to the understanding of the generally harmless host-EBV interaction and may be extrapolated to the fate of normal B cells after EBV infection. The phenotype of EBV negative BL lines resembles resting B cells. LÄS MER