Sökning: "Brain stem stroke"

Visar resultat 21 - 25 av 27 avhandlingar innehållade orden Brain stem stroke.

1. 21. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia

   Författare :Gunnar Andsberg; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; Neurology; animal behaviour; striatum; stereology; immunohistochemistry; focal cerebral ischemia; nerve growth factors; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Sammanfattning : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. LÄS MER

3. 22. Interactions between mouse CNS cells : microglia and neural precursor cells

   Författare :Johan Aarum; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Aggregate cultures; cell markers; CNS; differentiation; fetal; immunohistochemistry; microglia; migration; neural stem cells; phage display; precursor; Slit.;

   Sammanfattning : The mammalian central nervous system (CNS) contains a variety of cells, all specialized to perform different functions. Most numerous are the three types of glia cells, whose basic role is to support the signaling units of the CNS, the neurons. LÄS MER

4. 23. In vivo responses of neural progenitor cells to extracellular matrix signaling under pathological conditions

   Författare :Reza Motalleb; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptide Amphiphiles; Biomaterial; Tenascin - C; RGDS; RHAMM; Reactive Gliosis; Rostral Migratory Stream; Extracellular Matrix;

   Sammanfattning : The adult brain has an inherently low capacity for tissue regeneration, and neurons lost to disease or injuries are normally not replaced. This becomes especially apparent when stroke or brain trauma occurs. The discovery of neurogenesis and neural stem cells in the adult brain has opened up new avenues for treatment of the injured brain. LÄS MER

5. 24. The neurogenic potential of astrocytes : a story of transformation and renewal

   Författare :Giuseppe Santopolo; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : To not simply repair an organ, but to regenerate and fully recover its function, like there was no injury at all, that is the goal of regenerative medicine. Of all the organs in the human body, the most delicate and difficult to regenerate is the human brain. LÄS MER

7. 25. Generation of cortical neurons through reprogramming technology

   Författare :Giedre Miskinyte; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cortex; Reprogramming; human ES cells; transcription factor programming; cortical projection neurons; Human adult cortical slices;

   Sammanfattning : The human cortex is affected by several debilitating acute and chronic neurodegenerative disorders such as stroke, traumatic brain injury, amyotrophic lateral sclerosis and Alzheimer’s disease, which target specific types of cortical neurons. Emerging evidence indicates that stem cells and reprogrammed cells can be used to generate human cortical neurons both for cell replacement by transplantation, and for disease modeling and drug screening. LÄS MER