Sökning: "Brain stem stroke"

Visar resultat 11 - 15 av 27 avhandlingar innehållade orden Brain stem stroke.

  1. 11. Neurogenesis and gliogenesis after focal brain ischemia. Modulation by enriched environment and exercise

    Författare :Mila Komitova; Göteborgs universitet; []
    Nyckelord :astrocyte; hippocampus; neural progenitor cells; neural stem cells; neurogenesis; neurotrophins; rat; regeneration; rehabilitation; stroke;

    Sammanfattning : New neurons are formed from dividing neural stem cells in restricted areas in the adult mammalian brain: the dentate gyrus of the hippocampal formation (DG) and the forebrain subventricular zone (SVZ). New glia also form constitutively and seem to be important for neuronal function. LÄS MER

  3. 12. The Foxf2 gene in development and disease

    Författare :Azadeh Reyahi; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Foxf2; Pericyte; brain development; stroke;

    Sammanfattning : The Foxf2 gene in development and disease Azadeh Reyahi Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE 405 30, Göteborg, Sweden Abstract In this thesis I present our recent data on the involvement and the mechanism of action of the forkhead transcription factor Foxf2 in development of the brain microvasculature, formation of the blood-brain barrier, control of the intestinal stem cell niche, and fusion of the secondary palate. The potential clinical signifi- cance of these findings is strengthened by a correlation between Foxf2 expres- sion and intestinal adenoma formation, and by association between genetic vari- ants in human FOXF2 and incident stroke. LÄS MER

  4. 13. Inflammation and Stem Cell Therapy for Stroke

    Författare :Ruimin Ge; Lund Neurologi; []
    Nyckelord :;

    Sammanfattning : Ischemic stroke is a leading cause of death and disability worldwide. Currently, there is no treatment that can promote recovery in the chronic phase. It has been shown that neurogenesis occurs in ischemic striatum in rodents and probably also in humans. LÄS MER

  5. 14. Derivation, propagation and differentiation of human stem and progenitor cells

    Författare :Mathilda Zetterström Axell; Göteborgs universitet; []
    Nyckelord :Human embryonic stem cells; neural progenitor cells; stem cells; differentiation; propagation; migration; cell culturing; rostral migratory stream; electrospun scaffolds;

    Sammanfattning : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. LÄS MER

  7. 15. Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain

    Författare :Nina Rosenqvist; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; Neurology; neuropsychology; ChIP; rat; transgene; insulator; differentiation; GFP; lentivirus; DNA methylation; histone deacetylation; chromatin; expression; silencing; stem cell; progenitor; gene therapy; neurofysiologi; neuropsykologi; CNS; transplantation;

    Sammanfattning : The use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. LÄS MER