Sökning: "Brain graph"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Brain graph.
1. The architecture of the aging brain : functional reorganization, structural changes, and the role of dopamine receptors
Sammanfattning : Aging is associated with reorganization of functional brain architecture, potentially leading tocognitive decline in older age. However, the mechanisms responsible for alterations in functionalbrain architecture remain poorly understood. LÄS MER
2. Random geometric graphs and their applications in neuronal modelling
Sammanfattning : Random graph theory is an important tool to study different problems arising from real world.In this thesis we study how to model connections between neurons (nodes) and synaptic connections (edges) in the brain using inhomogeneous random distance graph models. LÄS MER
3. Modern multimodal methods in brain MRI
Sammanfattning : Magnetic resonance imaging (MRI) is one of the pillars of modern medical imaging, providing a non-invasive means to generate 3D images of the body with high soft-tissue contrast. Furthermore, the possibilities afforded by the design of MRI sequences enable the signal to be sensitized to a multitude of physiological tissue properties, resulting in a wide variety of distinct MRI modalities for clinical and research use. LÄS MER
4. Image and Data Analysis for Spatially Resolved Transcriptomics : Decrypting fine-scale spatial heterogeneity of tissue's molecular architecture
Sammanfattning : Our understanding of the biological complexity in multicellular organisms has progressed at tremendous pace in the last century and even more in the last decades with the advent of sequencing technologies that make it possible to interrogate the genome and transcriptome of individual cells. It is now possible to even spatially profile the transcriptomic landscape of tissue architectures to study the molecular organization of tissue heterogeneity at subcellular resolution. LÄS MER
5. Graph theory based approaches for gene prioritization in biological networks : Application to cancer gene detection in medulloblastoma
Sammanfattning : Networks provide an intuitive and highly adaptable means to model relationships between objects. When translated to mathematical graphs, they become further amenable to a plethora of mathematical operations that allow a detailed study of the underlying relational data. LÄS MER