Sökning: "Bröstcancer-genetik"

Visar resultat 11 - 15 av 81 avhandlingar innehållade ordet Bröstcancer-genetik.

  1. 11. Molecular Subtypes of Melanoma. Biological and Clinical Significance

    Författare :Helena Cirenajwis; Bröstcancer-genetik; []
    Nyckelord :Melanoma; molecular subtypes; gene expression; next generation sequencing;

    Sammanfattning : Cutaneous malignant melanoma (CMM) is the most lethal form of skin cancer and its incidence has increased faster than that of any other cancer, rendering it a major public health problem worldwide. High-throughput screenings have opened the door to a new scientific world, which enables molecular-based characterization of large cancer cohort collections. LÄS MER

  3. 12. Pathophysiology of 5-fluorouracil induced cardiotoxicity : a clinical and experimental study

    Författare :Magdalena Cwikiel; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; cell culture.; scanning and transmission electron microscopy; endothelium; lipid peroxidation; free radical; fibrinogen; 5-fluorouracil; blood and plasma viscosity; cardiotoxicity; cancerology; Cytologi; onkologi; cancer; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : This thesis concerns the pathophysiology of 5-fluorouracil (5-FU) induced cardiotoxicity. The aim of the clinical studies was to determine whether hemorheological factors might explain 5-FU cardiotoxicity (I) and if the syndrome was associated with free radical (FR) generation and lipid peroxidation (II). LÄS MER

  4. 13. Testicular cancer; gonadal, sexual and psychological aspects of the disease and its treatment

    Författare :Jakob Eberhard; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; depression; sexual dysfunction; hypogonadism; testicular cancer; fertility; anxiety; androgen receptor;

    Sammanfattning : The survival rates among testicular germ cell cancer (TGCC) patients have dramatically increased and more than 95 % are cured. The question of quality of life of the survivors is, therefore, important. The TGCC treatment, and thereby its side-effects may vary. LÄS MER

  5. 14. Prognostic and Predictive Markers in Primary Breast Cancer - Quality Assurance and Long-term Effects of Adjuvant tamoxifen Treatment

    Författare :Maria Ekholm; Bröstcancer-genetik; []
    Nyckelord :Breast cancer; Quality assurance; Tamoxifen; Long-term effects;

    Sammanfattning : .... LÄS MER

  7. 15. Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence

    Författare :Jacob Engellau; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth pattern; time-dependence; P-glycoprotein Pgp ; CD44; β-catenin; cyclin A; bcl-2; p53; Ki-67; immunohistochemistry IHC ; whole-tumor sections; tissue microarray TMA ; Soft tissue sarcoma; prognostic factors; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. LÄS MER