Sökning: "Bone marrow-derived stromal cells"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Bone marrow-derived stromal cells.

1. 1. Mesenchymal stromal cells in lung tissue

   Författare :Sara Rolandsson Enes; Lungbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stromal cells; lung transplantation; bronchiolitis obliterans syndrome; obliterative bronchiolitis; extracellular matrix;

   Sammanfattning : Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative properties. During recent years, the interest in using MSC for clinical approaches for various diseases have increased. LÄS MER

3. 2. Mesenchymal stem cells for repair of the peripheral and central nervous system

   Författare :Maria Brohlin; Mikael Wiberg; Martin Birchall; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bone marrow-derived stromal cells; Schwann cells; Peripheral nerve injury; Spinal cord injury; Neurotransplantation; anatomi; Human Anatomy; cell research; cellforskning;

   Sammanfattning : Bone marrow-derived mesenchymal stem cells (MSC) have been shown to provide neuroprotection after transplantation into the injured nervous system. The present thesis investigates whether adult human and rat MSC differentiated along a Schwann cell lineage could increase their expression of neurotrophic factors and promote regeneration after transplantation into the injured peripheral nerve and spinal cord. LÄS MER

4. 3. Immunoregulatory effects of placenta-derived decidual stromal cells

   Författare :Tom Erkers; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated and used as cellular therapy for inflammatory conditions following hematopoietic stem cell transplantation (HSCT). LÄS MER

5. 4. Phenotypic and functional analysis of the mesenchymal stromal cell compartment in the thymus

   Författare :Katarzyna Sitnik; Slemhinnans immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thymus; mesenchymal cells; retinoic acid; thymic epithelial cells;

   Sammanfattning : T cells are key cellular components of the adaptive immune system that play a critical role in our defense against pathogens and cancer but also contribute to pathology in the setting of chronic inflammation and autoimmunity. The thymus constitutes the body's major T cell production site, where bone marrow-derived progenitors migrate in a co-ordinated fashion through anatomically distinct cortical and medullary regions that are composed of epithelial and mesenchymal stromal elements. LÄS MER

7. 5. Mesenchymal stromal/stem cells : expansion, engraftment and immune modulation

   Författare :Håkan Samuelsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Due to their production of hematopoietic growth factors and their immunomodulatory capacity, bone marrow-derived mesenchymal stromal/stem cells (MSC), are a promising tool in the procedure of hematopoietic stem cell transplantation (HSCT). Seven patients undergoing allogeneic HSCT were co-infused with MSC. LÄS MER