Sökning: "Bone Morphogenetic Protein BMP"
Visar resultat 1 - 5 av 37 avhandlingar innehållade orden Bone Morphogenetic Protein BMP.
1. Craniofacial bone reconstruction with bone morphogenetic protein-2
Sammanfattning : Bone defects in the craniofacial area are a clinical challenge and can be the result of trauma, tumour resection or congenital malformations. The golden standard for reconstruction is autologous bone grafts, but bone may not always be readily available and donor-site morbidity might follow. LÄS MER
2. Molecular regulators in cartilage and bone formation
Sammanfattning : Cartilage functions as a scaffold for bone formation during development. This process, endochondral ossification, is regulated by systemic hormones and local growth factors. LÄS MER
3. The Anabolic - Anti-catabolic Paradigm of Augmenting Skeletal Regeneration: A Bone Quality Perspective
Sammanfattning : Successful fracture repair is a complex series of coordinated processes leading to regeneration of new bone to bridge the fracture site, remodelling of the newly formed bone and restoration of skeletal function. Disruption of these processes occurs in approximately 10% of all fractures and leads to delayed or failed healing requiring surgical interventions, increased complication rates, prolonged rehabilitation and high morbidity. LÄS MER
4. Bone Enhancement with BMP-2 for Safe Clinical Translation
Sammanfattning : Bone morphogenetic protein-2 (BMP-2) is considered a promising adjuvant for the treatment of bone regeneration. However, BMP-2 delivery in a conventional collagen scaffold needs a high dose to achieve an effective outcome. Moreover, such dosage may lead to serious side effects. LÄS MER
5. Bone Regeneration with Cell-free Injectable Scaffolds
Sammanfattning : Bone is a remarkable multifunctional tissue with the ability to regenerate and remodel without generating any scar tissue. However, bone loss due to injury or diseases can be a great challenge and affect the patient significantly. Autologous bone grafting is commonly used throughout the world. LÄS MER