Sökning: "Bogdan O Popescu"

Hittade 1 avhandling innehållade orden Bogdan O Popescu.

1. 1. Cell death and signal transduction pathways in Alzheimer's disease : the role of presenilin 1

   Författare :Bogdan O Popescu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Mutated presenilins (PSs) may cause familial Alzheimer's disease (FAD) by altering neuronal signal transduction pathways, by increasing AP production or by triggering a number of proapoptotic mechanisms. The present thesis explores mechanisms by which PSs regulate signal transduction and cell death with relevance to AD. LÄS MER