Sökning: "Body protein"

Visar resultat 6 - 10 av 743 avhandlingar innehållade orden Body protein.

1. 6. An evolutionary basis for protein design and structure prediction

   Författare :Christoffer Norn; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Biophysics; Protein design; Protein structure prediction;

   Sammanfattning : The sequence diversity of protein families is a result of the biophysical selection pressures that shaped their evolutionary history. Among the dominant pressures is selection for protein thermostability, which in itself is an attractive target in protein engineering because of its importance for various biopharmaceutical properties, the performance of industrial enzymes, and the ability to design new protein functions. LÄS MER

3. 7. Adipocyte phosphatases and the antilipolytic action of insulin

   Författare :Svante Resjö; Signaltransduktionsforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein phosphorylation; protein purification; adipose tissue; PP2A; protein phosphatase; PDE3B; phosphodiesterase 3B; Insulin signalling; antilipolysis; Klinisk biologi; Clinical biology; PKB; protein kinase B;

   Sammanfattning : Adipose tissue is the main site of energy storage of the body and an important endocrine organ. Knowledge of the regulation of fat metabolism and the endocrine factors secreted by the adipocyte is crucial for the understanding of diseases such as obesity and diabetes. Insulin is the main antilipolytic hormone. LÄS MER

4. 8. The effect of protein intake and physical exercise on energy turnover and substrate utilisation at energy balance in man

   Författare :Anders H. Forslund; Uppsala universitet; []
   Nyckelord :Medical sciences; Body composition; carbohydrate; energy turnover; fat; protein; stable isotopes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Nutrition; näringslära;

   Sammanfattning : The principal goal of the thesis has been to evaluate the effect of protein intake and physical exercise on energy turnover and substrate utilisation. Body composition assessment is of importance as an indicator of the energy balance. Therefore, in the first study the aim was to develop new models to estimate body composition more accurately. LÄS MER

5. 9. Structural Details of Human Aquaporin Regulation : Three stories of three aquaporins

   Författare :Veronika Nesverova; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aquaporin; membrane proteins; protein trafficking; water channel; aquaporin 0; aquaporin 5; aquaporin 2; cryo-EM; protein phosphorylation; protein-protein interaction; aquaporin regulation; aquaporins;

   Sammanfattning : Every cell is surrounded by a thin plasma membrane, protecting it from its surrounding. Specialized protein channels and transporters are embedded in this membrane, ensuring selective transport of molecules in and out of the cells. To maintain optimal hydration, water channels called aquaporins (AQPs) are present in every cell of our body. LÄS MER

7. 10. Fluorescent Probes and Protein Misfolding: Methods and Applications

   Författare :Irem Nasir; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein misfolding; fluorophores; filter-trap; site-specific fluorophore labeling; amyloid-beta; microscopic rate constants; solvatochromic probes; alpha-synuclein; lipid vesicles; nanoparticles; protein adsorption;

   Sammanfattning : Protein misfolding is a frequently occurring event in living cells and without the quality control, the consequences are disasterous. In this thesis, we studied protein misfolding in vitro by employing a variety of fluorophores, to either detect the highly ordered aggregates of intrinsically disordered proteins/peptides or slight misfolding of a natively folded protein. LÄS MER