Sökning: "Blood substitutes"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Blood substitutes.

  1. 1. Towards New Generation of Hemoglobin-Based Blood Substitutes

    Författare :Sandeep Chakane; Tillämpad biokemi; []
    Nyckelord :hemoglobin; Fetal hemoglobin; Hemoglobin-based oxygen carrier; DNA cleavage; comet assay;

    Sammanfattning : Blood transfusion is a clinically significant and crucial process, which saves millions of lives every year. However,shortage of donated blood and the risk of virus transmission through transfusible blood seriously affect theavailability of the blood. LÄS MER

  3. 2. Human Fetal Hemoglobin : Biochemical Characterization and Recombinant Production

    Författare :Khuanpiroon Ratanasopa; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Blood substitutes; HBOCs; HbF; recombinant hemoglobin; pseudoperoxidase; ITC; haptoglobin;

    Sammanfattning : Blood transfusion is a common medical procedure when oxygen supply in the body is impaired. However, blood transfusion is not always without risks. The uncontrolled spreading of blood borne pathogens such as HIV or hepatitis B and C virus has urged researchers to look for “blood substitutes”. LÄS MER

  4. 3. A radical view of haemoglobin - protein engineering and characterisation

    Författare :Marie Grey; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; His-Gln tagging; protein purification; blood substitutes; radical scavenging; superoxide dismutase; E. coli; diglobin; Haemoglobin; protein engineering; aqueous two-phase systems; hydrophobic interaction chromatography;

    Sammanfattning : In recent years shortages of donated blood have become a growing problem for health care systems world-wide. Blood substitutes based on human haemoglobin (Hb) could potentially ameliorate this situation. However, clinical trials have indicated problems due to e.g. LÄS MER

  5. 4. Toward a tissue engineered blood vessel. Cell cultivation, hemodynamic influences and matrix production

    Författare :Sepideh Heydarkhan-Hagvall; Göteborgs universitet; []
    Nyckelord :tissue engineered blood vessel; co-culture vascular cells; angiogenic factors; ; hemodynamic; extracellular matrix; stem cells;

    Sammanfattning : Cardiovascular diseases are the leading causes of mortality in the western world. Thereplacement or repair of diseased blood vessels with human autografts (vein or arteries) orsynthetic vascular grafts (ePTFE or Dacron) has become a routine treatment. Autologous graftsare not always available in all patients. LÄS MER

  7. 5. Biomedical Applications of Bacterial Cellulose Fermentation, Morphology and Surface Properties

    Författare :Aase Katarina Bodin; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biocompatibility; xyloglucan epitopes; mechanical properties; cell adhesion; tubular fermentation; morphology; Bacterial cellulose; surface properties; meniscus mold; crystal formation.; ozonation; adsorption;

    Sammanfattning : Because average life expectancy has increased and peoples lifestyles have changed, degenerative diseases have become a critical issue. The demand for biomedical materials to replace or improve major body systems (skeletal, circulatory and nervous, etc.) will increase as people strive to maintain good quality of life. LÄS MER