Sökning: "Blood platelets"

Visar resultat 1 - 5 av 142 avhandlingar innehållade orden Blood platelets.

1. 1. Platelets : intracellular signalling and cellular interaction

   Författare :Magnus Grenegård; Hans Gyllenhammar; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Activation of platelets is essential to prevent excessive blood loss at the site of vascular injury. These highly reactive cell fragments are also involved in several pathological conditions, in particular arterial thrombosis, which, in the coronary vessels, can lead to reduced blood flow, vessel occlusion and myocardial infarction. LÄS MER

3. 2. Platelets : with special reference to platelet density subpopulations, stable coronary heart disease and atrial fibrillation

   Författare :Micha Milovanovic; Claes Hallert; Petter Järmeo; Tomas Lindahl; David Erlinge; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The current thesis was divided into two parts. Basic platelet research is the topic of the first section. The subsequent clinical part examines platelet reactivity in stable angina pectoris (AP) and in atrial fibrillation.Platelet heterogeneity was investigated in the first section (papers 1 and 2). LÄS MER

4. 3. Circulating platelets : a novel liquid biopsy source for cancer diagnostics and therapy stratification

   Författare :Lee-Ann Tjon-Kon-Fat; Jonas Nilsson; Pernilla Wikström; Michiel Pegtel; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; biomarkers; liquid biopsy; therapy stratification; personalised medicine; Prostate cancer;

   Sammanfattning : As conventional tissue biopsies have several drawbacks, much effort has been directed toward the development of minimal-invasive liquid biopsy platforms for detecting and profiling cancer.Platelets are the second most abundant cells in blood and have very versatile functions both in physiological and pathophysiological conditions. LÄS MER

5. 4. Crosstalk Between Activated Platelets and the Complement System

   Författare :Osama A. Hamad; Bo Nilsson; Kristina Ekdahl-Nilsson; Lennart Truedsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER

7. 5. Effect of Surface Nanotopography on Blood-Biomaterial Interactions

   Författare :Natalia Ferraz; Marjam Ott; Jaan Hong; Jan Carlsson; Tom Eirik Mollnes; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanoporous alumina; nanotopography; biomaterial; platelets; complement system; macrophages; whole blood; inflammatory response; Chemistry; Kemi; Immunobiology; Immunbiologi; Immunologi; Immunology; Materialvetenskap; Materials Science;

   Sammanfattning : Biologically inspired materials are being developed with the aim of improving the integration of medical implants and minimizing non-desirable host reactions. A promising strategy is the design of topographically patterned surfaces that resemble those found in the extracellular environment. LÄS MER