Sökning: "Blood coagulation factors"

Visar resultat 6 - 10 av 61 avhandlingar innehållade orden Blood coagulation factors.

  1. 6. Tissue Factor and CD40 Ligand : Markers for the Interplay of Coagulation and Inflammation in the Acute Coronary Syndrome

    Författare :Anders Mälarstig; Agneta Siegbahn; Lars Wallentin; Taavo Tenno; Fiona Green; Uppsala universitet; []
    Nyckelord :Molecular medicine; tissue factor; CD40 ligand; gene expression; single nucleotide polymorphism; acute coronary syndrome; myocardial infarction; coagulation; inflammation; Molekylärmedicin;

    Sammanfattning : BACKGROUND: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. CD40 ligand is another membrane molecule, which ligates to cell types associated with atherosclerotic plaques thereby mediating intraplaque inflammation and weakening of the fibrous cap. LÄS MER

  3. 7. Systemic inflammatory activation during cardiac Surgery. Influence of cardiopulmonary bypass management and patient factors

    Författare :Martin Westerberg; Göteborgs universitet; []
    Nyckelord :cardiopulmonary bypass; inflammatory response; coagulation; CABG; cardiotomy suction; cytokines;

    Sammanfattning : Cardiac surgery with cardiopulmonary bypass is accompanied by a prominent systemic inflammatory and hemostatic activation, which may contribute to postoperative complications. Aims: To investigate if selection of cardiopulmonary bypass (CPB) system and management of cardiotomy suction (CTS) and mediastinal shed blood (MSB) affect systemic inflammatory response. LÄS MER

  4. 8. The role of platelets in whole blood coagulation

    Författare :Sofia Ramström; Nils Olav Solum; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The body's first line of defence against bleeding is the platelets, small cell fragments with multiple roles in the coagulation process. The platelets are patrolling our blood vessels, looking for damage in the endothelial cell layer, to which they attach and transform, recruit more platelets and assemble the plasma coagulation proteases on their surfaces. LÄS MER

  5. 9. Modifiable risk factors, blood proteins, and venous thromboembolism

    Författare :Shuai Yuan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Venous thromboembolism (VTE) refers to blood clots in the veins, which is an underappreciated vascular disease that can cause disability and mortality. Although some triggers for VTE (e.g. LÄS MER

  7. 10. Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

    Författare :Gunnar Nilsson; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; protein C; mortality; intensive care; health economics; global haemostatic tests; blood coagulation disorders; APC-PCI complex; abdominal aortic aneurysm operation; antithrombin; Medicin människa och djur ;

    Sammanfattning : Critically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. LÄS MER