Sökning: "Björn Önfelt"

Visar resultat 6 - 10 av 12 avhandlingar innehållade orden Björn Önfelt.

  1. 6. Modeling and Data Analysis in Cellular Biophysics

    Författare :Jacob Kowalewski; Hjalmar Brismar; Anita Aperia; Björn Önfelt; Karl-Eric Magnusson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; Biofysik;

    Sammanfattning : Cellular biophysics deals with the physical aspects of cell biology. This thesis presents a number of studies where mathematical models and data analysis can increase our understanding of this field. LÄS MER

  3. 7. Microscopy-based single-cell in vitro assays for NK cell function in 2-D and 3-D

    Författare :Per Erik Olofsson; Björn Önfelt; Khakoo Salim; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Sammanfattning : Natural killer (NK) cells are effector cells of the innate immune system that are responsible for mediating cellular cytotoxicity against virally infected or neoplastically transformed cells. NK cell subsets are defined by their expression of certain cell-surface markers, and are usually related to activation and developmental status. LÄS MER

  4. 8. Quantitative approaches to studying NK cell functional heterogeneity

    Författare :Per Olofsson; Björn Önfelt; Adnane Achour; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : It is commonly stated that the cell is the smallest functional unit of life. By analogy, then, the immune cell is the smallest functional unit of the immune system. LÄS MER

  5. 9. Mechanisms regulating Natural Killer Cell Cytotoxicity

    Författare :Hanna van Ooijen; Björn Önfelt; Karl-Johan Malmberg; Karolin Guldevall; Morgan Huse; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Natural Killer cell; Live-cell microscopy; Single cell; 3D; Microwell;

    Sammanfattning : Over the last 50 years, cancer survival rates have steadily improved thanks to earlier detection and novel treatment regimens. For example, drugs that act on the immune system, so-called immunotherapy, have drastically increased the prospect of survival for patients suffering from some of the most aggressive cancer types including advanced malignant melanoma. LÄS MER

  7. 10. Imaging-based methods for NK cell studies at the single-cell level

    Författare :Quentin Verron; Björn Önfelt; Niklas Sandström; Michael Dustin; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; NK cells; microscopy; single-cell; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Sammanfattning : The immune system provides defense against infectious agents such as viruses, bacteria and parasites. Besides eliminating extracellular agents, the immune system also constantly monitors our own cells for signs of transformation, including tumor development and virus infection. LÄS MER