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1. 1. Analgetic and algetic effects of adenosine in healthy volunteers and patients with coronary disease

   Författare :Bita Sadigh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Angina pectoris; silent myocardial ischemia; opioid; gender; preconditioning;

   Sammanfattning : Background: Adenosine is a bimodal neuromodulator with algesic and analgesic effects. The different effects of adenosine are partly due to the route of administration. Low-dose adenosine infusion induces analgesia at the same magnitude as morphine, while adenosine as bolus injection induces chest pain, similar in character as angina pectoris. LÄS MER