Sökning: "Biotransformation"
Visar resultat 16 - 20 av 55 avhandlingar innehållade ordet Biotransformation.
16. Carcinogenic polycyclic aromatic hydrocarbons : theoretical, molecular, in vitro and cellular characterization of biotransformation and DNA damage
Sammanfattning : Polycyclic aromatic hydrocarbons (PAHs) are widespread mutagenic and carcinogenic environmental pollutants, which require metabolic activation to electrophilic intermediates and subsequent covalent binding to critical targets in DNA to elicit their biological activity. Bayand fjord-region diol epoxides (DEs) have been identified as the ultimate mutagenic and carcinogenic metabolites of PAHs. LÄS MER
17. Detoxification mechanisms in fish -regulation and function of biotransformation and efflux in fish exposed to pharmaceuticals and other pollutants
Sammanfattning : .... LÄS MER
18. Microbial and enzymatic syntheses of polymer building blocks through selective transformations of polyols and furans
Sammanfattning : AbstractTransition from fossil- to bio-based economy is a critical step towards reduction of greenhouse gas emissions and climate change, and hence for achievement of sustainable communities and environment. In order to be fossil-free, the chemical and material industry is in need of carbon-neutral building blocks from renewable resources for the diverse array of products that are currently produced from olefins and aromatics. LÄS MER
19. Transition Metal-Mediated Selective Functionalizations of Bio-Derived Building Blocks
Sammanfattning : In order to transition to a more sustainable chemical industry, it is necessary to replace the fossil starting materials that are largely used today with renewable ones. Starting materials available from abundant natural sources, or which can be efficiently produced via a biotransformation, are of high interest in this regard. LÄS MER
20. Toxicity of smokeless tobacco in human oral epithelium with emphasis on carcinogen metabolism and regulation of programmed cell death
Sammanfattning : The oral mucosa is globally a common site for cancer development. Primary risk factors include tobacco smoking and alcohol consumption whereas the contribution from usage of smokeless tobacco remains debated. LÄS MER