Sökning: "Bioteknologi"
Visar resultat 6 - 10 av 985 avhandlingar innehållade ordet Bioteknologi.
6. Bifunctional ADAPTs: Opportunity for serological Half-life extension and Targeted therapy
Sammanfattning : Small engineered scaffold proteins (ESPs) gain more and more popularity as biological drugs, due to their specificity and applicability in diagnostics and therapy. Thanks to their high stability, low immunogenicity and low production cost, they present themselves as a promising alternative to the market-leading antibodies. LÄS MER
7. Centrifugal microfluidics-based point of care diagnostics at resource limited settings
Sammanfattning : Advancements in medical diagnostics have allowed us to understand the underlying mechanism and treat the root cause for many diseases which had been causing morbidity and mortality up until this point in human history. Furthermore, many of the standard diagnostic procedures have now been transformed to provide answers at or near the point-of-care. LÄS MER
8. Affinity assays for profiling disease-associated proteins in human plasma
Sammanfattning : Affinity-based proteomics offers opportunities for the discovery and validation of disease-associated proteins in human body fluids. This thesis describes the use of antibody-based immunoassays for multiplexed analysis of proteins in human plasma, serum and cerebrospinal fluid (CSF). LÄS MER
9. Neuroproteomic profiling of human body fluids
Sammanfattning : This thesis provides results from affinity based studies where human body fluids were profiled to find markers for neurological diseases. Both proteins and autoantibodies were analysed using microarray technologies that can profile hundreds of analytes and hundreds of samples in parallel using small sample volumes. LÄS MER
10. Proteomic strategies for blood biomarker development in rare dystrophinopathies
Sammanfattning : Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are two rare genetic disorders of the family dystrophinopathy. They are both caused by the lack of, or reduced production of, the protein dystrophin. LÄS MER