Sökning: "Bioteknologi"
Visar resultat 16 - 20 av 985 avhandlingar innehållade ordet Bioteknologi.
16. The ADAPT scaffold as a tool for diagnostic imaging and targeted therapy
Sammanfattning : Molecular recognition, or the specific interactions between a protein and its ligand, is central to biology and a key factor for many different clinical and technical applications. Despite antibodies being only one of many different affinity proteins, it has by far been the most successful. LÄS MER
17. Human iPSC-based models of theCNS: attaining cellular biofidelitythrough conventional and advancedculture systems
Sammanfattning : Brain development is a highly orchestrated process that entails changes in microenvironmental cues and growth factor gradients, which set the tempo for proper development of the rudimentary structures of the brain and the generation of neurons,astrocytes, and oligodendrocytes. Another intricate feature of the brain is the bloodbrain barrier (BBB). LÄS MER
18. Engineering strategies for ABD-derived affinity proteins for therapeutic and diagnostic applications
Sammanfattning : Small stable protein domains are attractive scaffolds for engineering affinity proteins due to their high tolerance to mutagenesis without loosing structural integrity. The albuminbinding domain is a 5 kDa three-helix bundle derived from the bacterial receptor Protein G with low-nanomolar affinity to albumin. LÄS MER
19. Engineering the extracellular matrix to model diseases and orchestrate regeneration
Sammanfattning : The extracellular matrix is not only a scaffold to which cells attach, but it is also a matrix that communicates cell signals. Because of the interplay between cells and the extracellular matrix, changes in the extracellular matrix can steer cell fate. LÄS MER
20. Autoantibody profiling in autoimmune diseases
Sammanfattning : Autoimmune disease diagnosis and definition of prognosis can be challenging. Patients with the same autoimmune disease could present with very heterogeneous symptoms. Therefore, there is a need to understand the disease better to improve patients’ diagnosis, and classification, and tailor the treatment. LÄS MER