Sökning: "Biomedical sciences"
Visar resultat 6 - 10 av 486 avhandlingar innehållade orden Biomedical sciences.
6. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities
Sammanfattning : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. LÄS MER
7. Tunable and modular assembly of polypeptides and polypeptide-hybrid biomaterials
Sammanfattning : Biomaterials are materials that are specifically designed to be in contact with biological systems and have for a long time been used in medicine. Examples of biomaterials range from sophisticated prostheses used for replacing outworn body parts to ordinary contact lenses. Currently it is possible to create biomaterials that can e.g. LÄS MER
8. Extracellular Matrix Based Materials for Tissue Engineering
Sammanfattning : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. LÄS MER
9. High-Tc SQUIDs for biomedical applications: immunoassays, MEG, and ULF-MRI
Sammanfattning : This thesis describes high transition temperature superconducting quantum interference devices (high-Tc SQUIDs) for magnetic immunoassays (MIAs), magnetoencephalography (MEG) and ultra-low field magnetic resonance imaging (ULF-MRI).High-Tc dc SQUID sensors were fabricated in single layers of YBa2Cu3O7−δ deposited by pulsed laser deposition and patterned using photolithography on 10×10 mm2 SrTiO3 bicrystal substrates. LÄS MER
10. Luminescence Spectroscopy For Biomedical Applications
Sammanfattning : This work presents optical methods utilizing visible light for characterization of biological tissue during diagnostics and treatment processes. The main aim has been to improve the therapeutic outcome of treatment modalities in in vivo studies. LÄS MER