Sökning: "Biomarkers"

Visar resultat 16 - 20 av 1321 avhandlingar innehållade ordet Biomarkers.

1. 16. Biomarkers in sepsis and other severe infections

   Författare :Helena Janols; Enheten för infektionssjukdomar; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunosuppression; myeloid-derived suppressor cells; T cells; dendritic cells; monocytes; sepsis; Biomarkers;

   Sammanfattning : Infectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. LÄS MER

3. 17. The Temporomandibular Joint in Juvenile Idiopathic Arthritis : Psychosocial, clinical, imaging and parotid saliva biomarkers

   Författare :Alexandra Dimitrijevic Carlsson; Per Alstergren; Kerstin Wahlund; Carin Starkhammar Johansson; Martina. Frodlund; Bijar Ghafouri; Robin Kahn; Malmö universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; Juvenile Idiopathic Arthritis; Magnetic resonance imaging; Orofacial pain; Parotid gland; Plasma; Psychological distress; Psychosocial; Saliva; Stress; Temporomandibular joint; Biomarkörer; Juvenil idiopatisk artrit; Käkled; Magnetisk resonanstomografi; Orofacial smärta; Saliv; Spottkörtel; Stress;

   Sammanfattning : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. The disease can affect the temporomandibular joint (TMJ) and cause orofacial growth disturbances, pain, and jaw dysfunction. TMJ arthritis is often asymptomatic and therefore a challenging joint to diagnose. LÄS MER

4. 18. Biomarkers of ionising radiation relevant to carcinogenesis : Dose, dose rate and LET dependency of the responses

   Författare :Milagrosa López Riego; Andrzej Wojcik; Lovisa Lundholm; Alexandros G. Georgakilas; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ionising radiation; low dose; low dose rate; linear energy transfer LET ; mixed beams; dose and dose rate effectiveness factor DDREF ; cancer; DNA damage response; biomarkers; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : A better understanding of the relationship between ionising radiation (IR) dose, dose rate and radiation quality, and the risk of stochastic effects would improve risk extrapolation from atomic bomb survivors’ data. Owing to insufficient statistical power of epidemiological studies to detect excess incidence of cancer following low doses of IR delivered at low dose rates (LDLDR), as typically encountered in most common human exposure scenarios, radiobiological experiments are fundamental to describe the biological effectiveness of LDLDR and to define the underlying molecular mechanisms. LÄS MER

5. 19. Paleoclimate and seasonality on Sumatra during the Late Glacial and Holocene : Insights from biomarkers and climate model simulations

   Författare :Lars Petter Hällberg; Malin Kylander; Frederik Schenk; Rienk Smittenberg; David Naafs; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Holocene; Late Glacial; biomarkers; organic geochemistry; climate model; hydrogen isotopes; stable isotopes; paleoclimate; alkanes; GDGT; brGDGT; H-GDGT; bacterial community shifts; paleothermometry; precipitation reconstruction; peat; geokemi; Geochemistry;

   Sammanfattning : Deep atmospheric convection in the Indo-Pacific Warm Pool (IPWP) is a key driver of the Hadley and Walker Circulations that modulate the Asian-Australian monsoons and the El Niño Southern Oscillation (ENSO). Temperature and rainfall seasonality, i.e. LÄS MER

7. 20. Biomarkers for Alzheimer's disease and the APOE polymorphism

   Författare :Ronald Lautner; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; Biomarkers; APOE; Cerebrospinal fluid; β-amyloid;

   Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia and cerebrospinal fluid (CSF) biomarkers reflecting the core pathology of AD are now widely used for diagnosis making, in particular β-amyloid[1-42] (Aβ42) reflecting amyloid plaque pathology, phosphorylated tau (P-tau) reflecting neurofibrillary tangle pathology and total tau (T-tau) reflecting general neurodegeneration. In addition, blood-based biomarkers for AD are in the pipeline with recent studies showing promising diagnostic potential. LÄS MER