Sökning: "Biology with specialization in Molecular Biology"

Visar resultat 16 - 20 av 179 avhandlingar innehållade orden Biology with specialization in Molecular Biology.

  1. 16. Molecular Metamorphosis in Transcriptional Regulation

    Författare :Malin Lüking; Johan Elf; Victor Muñoz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein-DNA interactions; Facilitated diffusion; Binding Kinetics; Molecular Simulations; Fluorescence Microscopy; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : The foundation of all life is the interaction of molecules. Molecular interaction occurs in the tightly packed cytoplasm. In this crowded environment, the molecules need to be able to establish stable interactions with specific interaction partners, and with specific ones only. LÄS MER

  3. 17. Meiotic Recombination in Human and Dog : Targets, Consequences and Implications for Genome Evolution

    Författare :Jonas Berglund; Matthew Webster; Kerstin Lindblad-Toh; Leif Andersson; Nadia Singh; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; recombination; biased gene conversion; CpG island; copy number variation; substitutions; methylation; Bioinformatics; Bioinformatik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Understanding the mechanism of recombination has important implications for genome evolution and genomic variability. The work presented in this thesis studies the properties of recombination by investigating the effects it has on genome evolution in humans and dogs. LÄS MER

  4. 18. Comparative Genomics in Diplomonads : Lifestyle Variations Revealed at Genetic Level

    Författare :Feifei Xu; Jan O. Andersson; Staffan G. Svärd; Matt Berriman; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; comparative genomics; Giardia intestinalis; Spironucleus salmonicida; Trepomonas; diplomonad; intestinal parasite; free-living; sexual recombination; hydrogenosome; horizontal gene transfer; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : As sequencing technologies advance genome studies are becoming a basic tool for studying an organism, and with more genomes available comparative genomics is maturing into a powerful tool for biological research. This thesis demonstrates the strength of a comparative genomics approach on a group of understudied eukaryotes, the diplomonads. LÄS MER

  5. 19. New Molecular Approaches to Glioblastoma Therapy

    Författare :Sathishkumar Baskaran; Sven Nelander; Karin Forsberg Nilsson; Silvia Marino; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; GBM; ZBTB16; PLZF; Heterogeneity; Proteasome inhibitors; Bortezomib; Pterostilbene; drug combinations; Oncology; Onkologi; Biological Research on Drug Dependence; Biologisk beroendeforskning; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. LÄS MER

  7. 20. Cyanobacterial Hydrogen Metabolism : Regulation and Maturation of Hydrogenases

    Författare :Ellenor Devine; Peter Lindblad; Karin Stensjö; Laurent Cournac; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cyanobacteria; hydrogenase; hydrogenase specific protease; maturation; regulation; transcriptional studies; hupW; hoxW; hyp; NtcA; CalA; Biology; Biologi; Molecular biology; Molekylärbiologi; Microbiology; Mikrobiologi; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

    Sammanfattning : In times with elevated CO2 levels and global warming there is a need of finding alternatives to carbon based energy carriers. One such environmental friendly solution could be H2 produced by living organisms. LÄS MER