Sökning: "Biology with specialization in Environmental Toxicology"
Visar resultat 11 - 15 av 15 avhandlingar innehållade orden Biology with specialization in Environmental Toxicology.
11. Azoles and Contaminants in Treated Effluents Interact with CYP1 and CYP19 in Fish
Sammanfattning : Numerous contaminants are present in mixtures in the aquatic environment. Among these are the azoles, a group of chemicals that includes both pharmaceuticals and pesticides. Azole fungicides are designed to inhibit lanosterol 14-demethylase (cytochrome P450 (CYP) 51), while other azoles are intended to inhibit aromatase (CYP19), i.e. LÄS MER
12. The Xenopus tropicalis model for developmental endocrine and reproductive toxicity : Histological and molecular endpoints for disrupted spermatogenesis
Sammanfattning : Endocrine disrupting chemicals (EDCs) are linked to adverse effects in both humans and wildlife. There are however, large knowledge gaps regarding cause-effect and dose-response relationships between the interference with endocrine pathways and adverse effects in the organism, especially at puberty and in subsequent generations. LÄS MER
13. Androgenic Effects of the Progestin Levonorgestrel in Three-spined Stickleback (Gasterosteus aculatus)
Sammanfattning : The extensive use of pharmaceuticals and their poor removal by wastewater treatment plants has led to the emergence of pharmaceutical compounds as global aquatic contaminants. Progestins, the synthetic analogues to progesterone, are receiving increasing attention as contaminants and have been shown to impair reproduction in fish and amphibians at low ng L-1 concentrations. LÄS MER
14. Developmental and Reproductive Toxicity of Progestagens in the Xenopus (Silurana) tropicalis Test System
Sammanfattning : Progestagenic compounds are emerging contaminants found in surface and ground water around the world. Information on the effects and potency of progestagens is needed in order to understand the environmental risks posed by these compounds. LÄS MER
15. Developmental neurotoxicity of persistent and non-persistent pollutants : Behavioral and neurochemical assessments of a perfluorinated compound, pesticides and interaction effects
Sammanfattning : The focus of this thesis was to investigate developmental neurotoxic effects of different persistent and non-persistent environmental pollutants, alone or in binary mixtures, when exposure occurs during a critical period of brain development, in mice. The compounds investigated included a perfluorinated compound, perfluorohexane sulphonate (PFHxS), and four different pesticides, endosulfan, cypermethrin, chlorpyrifos and carbaryl. LÄS MER
