Sökning: "Biologisk fysik"

Visar resultat 16 - 20 av 122 avhandlingar innehållade orden Biologisk fysik.

1. 16. Dynamics of the voltage-sensor domain in voltage-gated ion channels : Studies on helical content and hydrophobic barriers within voltage-sensor domains

   Författare :Christine S. Schwaiger; Erik Lindahl; Lynn Kamerlin; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; activation; deactivation; inactivation; voltage-sensor; VSD; Kv1.2- 2.1; F233; hydrophobic barrier; alpha-helix; 3 10 -helix; Biological physics; Biologisk fysik;

   Sammanfattning : Voltage-gated ion channels play fundamental roles in neural excitability and thus dysfunctional channels can cause disease. Understanding how the voltage-sensor of these channels activate and inactivate could potentially be useful in future drug design of compounds targeting neuronal excitability. LÄS MER

3. 17. Fluorescence Studies of Membranes -- Proteins and Lipids, their Dynamics and Interactions

   Författare :Johan Strömqvist; Jerker Widengren; Thorsten Wohland; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fluorescence correlation spectroscopy; cytokinesis; collision theory; protein-protein interactions; lipid dynamics; single-molecule experiment; Biological physics; Biologisk fysik;

   Sammanfattning : In this thesis, fluorescence spectroscopy was utilized to probe protein and lipid dynamics and interactions in their native, or close to native, environments. Thereby insight could be gained into the fundamentals of bacterial cell division and the innateimmune system. A particular focus has been devoted to fluorescence fluctuations. LÄS MER

4. 18. Experimental Studies of the Interaction of Atmospheric Aerosol Particles with Clouds and Fogs

   Författare :Göran Frank; Kärnfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; unipolar charger; Physics; DMA; differential mobility analyser; DAA; droplet aerosol analyser; fog microstructure; cloud microstructure; fog droplet; cloud droplet; cloud; fysisk instrumentering; fog; Metrologi; physical instrumentation; Metrology; Kärnfysik; Nuclear physics; Fysik; Fysicumarkivet A:2001:Frank;

   Sammanfattning : In this work, cloud and fog droplet formation was studied in three joint field experiments. The instrument, the droplet aerosol analyser (DAA), has also been further developed and verified as part of this work. The DAA is an instrument especially developed for studies of cloud and fog droplet formation and growth. LÄS MER

5. 19. Biological Laboratory X-Ray Microscopy

   Författare :Mikael Kördel; Hans Hertz; Ulrich Vogt; Jonas A. Sellberg; Rajmund Mokso; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; x-ray microscopy; laboratory x-ray microscopy; water window; biological; cell imaging; virus; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik; Optik och fotonik; Optics and Photonics;

   Sammanfattning : Soft x-ray microscopy in the water window (? ≈ 2.3 − 4.3 nm) is a powerful technique for high-resolution biological imaging. The strong natural contrast between carbon-based structures and water allows visualization of hydrated and unstained samples, while providing enough transmission through up to ∼ 10 μm of organic matter. LÄS MER

7. 20. Biochip design based on tailored ethylene glycols

   Författare :Andréas Larsson (Kaiser); Bo Liedberg; Tommy Nylander; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biosensor; biochip; poly ethylene glycol ; self-assembled monolayer; photopolymerisation; microarray; biomolecular interaction; explosives detection; Physics; Fysik;

   Sammanfattning : Studies of biomolecular interactions are of interest for several reasons. Beside basic research, the knowledge gained from such studies is also very valuable in for example drug target identification. Medical care is another area where biomolecules may be used as biomarkers to aid physicians in making correct diagnosis. LÄS MER