Sökning: "Biological physics"

Visar resultat 11 - 15 av 304 avhandlingar innehållade orden Biological physics.

  1. 11. Studies on the Role of Apoptosis in Kidney Diseases

    Författare :Linnéa Nilsson; Hjalmar Brismar; Anita Aperia; Lena Scott; Fredrik Palm; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; diabetic kidney disease; hyperglycemia; mesangial cells; microscopy; ouabain; podocytes; proximal tubule cells; RNA-seq; SGLT; Apoptos; diabetisk njursjukdom; hyperglykemi; mesangiala celler; mikroskopi; ouabain; podocyter; proximala tubuli celler; RNA-seq; SGLT; Biological Physics; Biologisk fysik;

    Sammanfattning : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. LÄS MER

  3. 12. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics

    Författare :Joachim Piguet; Horst Vogel; Ruud Hovius; Jerker Widengren; Antoine Triller; Switzerland Ecole Polytechnique Fédérale de Lausanne (EPFL); []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence; microscopy; plasma membrane; membrane proteins; membrane proteins diffusion; single-molecule imaging; single-molecule tracking; pentameric ligand-gated ion channels; nicotinic acetylcholine receptor; serotonin receptor; synapse; neuromuscular junction; post-synaptic scaffold; rapsyn; myopathies; fluorescent proteins; Förster resonance energy transfer; FRET imaging; protein-protein interactions; protein trafficking; photo-activatable proteins; Biological Physics; Biologisk fysik;

    Sammanfattning : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. LÄS MER

  4. 13. Statistical Physics of Protein Folding and Aggregation

    Författare :Giorgio Favrin; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Two State; Physics; Fysik; Statistics; operations research; programming; aktuariematematik; programmering; operationsanalys; actuarial mathematics; Statistik; Simulations; Aggregation; Protein Folding; Fysicumarkivet A:2004:Favrin;

    Sammanfattning : The mechanisms of protein folding and aggregation are investigated by computer simulations of all-atom and reduced models with sequence-based potentials. A quasi local Monte Carlo update is developed in order to efficiently sample proteins in the folded phase. LÄS MER

  5. 14. Variational Methods in Combinatorial Optimization and Phylogeny Reconstruction

    Författare :Henrik Jönsson; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; statistical physics; gravitation; relativity; annealing; variational; mean-field; phylogeny; constraint satisfaction; combinatorial optimization; maximum likelihood; Physics; Fysik; Mathematical and general theoretical physics; quantum mechanics; classical mechanics; klassisk mekanik; kvantmekanik; relativitet; statistisk fysik; termodynamik; Fysicumarkivet A:2001:Jönsson; Matematisk och allmän teoretisk fysik; thermodynamics;

    Sammanfattning : Algorithms based on the variational approach, as used in statistical physics, are developed. For constraint satisfaction problems a novel cost function, based on information-theoretic arguments, is introduced, and an algorithm similar to the mean-field annealing algorithm is proposed. LÄS MER

  7. 15. Laser Spectroscopy in Scattering Media for Biological and Medical Applications

    Författare :Linda Persson; Atomfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Instrumentation technology; Mät- och instrumenteringsteknik; Atom- och molekylärfysik; Atomic and molecular physics; Fysik; Physics; Monte Carlo simulations; Biomedical Optics; Scattering media; Gas measurements; Near infrared spectroscopy; Diode laser spectroscopy; Absorption spectroscopy;

    Sammanfattning : Tunable diode laser absorption spectroscopy can be utilised for gas detection in biological and medical applications. The common approach is to analyse transmitted light according to the Beer-Lambertian law. LÄS MER