Sökning: "Biological and Biomedical Physics"
Visar resultat 16 - 20 av 31 avhandlingar innehållade orden Biological and Biomedical Physics.
16. Fluorescence fluctuation studies of biomolecular interactions in solutions, biomembranes and live cells
Sammanfattning : Fluorescence spectroscopy and imaging have a very broad spectrum of applicationswithin the life sciences, in particular for detection and characterization ofbiomolecular dynamics and interactions in different environments. This thesis comprisesprojects that strive to further expand the information content extracted fromthe detected fluorescence, leading to sensitive readout parameters for studies ofbiomolecular dynamics and interactions. LÄS MER
17. Imaging-based methods for NK cell studies at the single-cell level
Sammanfattning : The immune system provides defense against infectious agents such as viruses, bacteria and parasites. Besides eliminating extracellular agents, the immune system also constantly monitors our own cells for signs of transformation, including tumor development and virus infection. LÄS MER
18. Characterisation of inputs and outputs of striatal medium spiny neurons in health and disease
Sammanfattning : Striatal medium spiny neurons (MSNs) play a crucial role in various motor and cognitive functions. They are separated into those belonging to the direct pathway (dMSNs) and the indirect pathway (iMSNs) of the basal ganglia, depending on whether they express D1 or D2 type dopamine receptors, respectively. LÄS MER
19. Synthesis of Polymeric Nanocomposites for Drug Delivery and Bioimaging
Sammanfattning : Nanomaterials have gained great attention for biomedical applications due to their extraordinary physico-chemical and biological properties. The current dissertation presents the design and development of multifunctional nanoparticles for molecular imaging and controlled drug delivery applications which include biodegradable polymeric nanoparticles, superparamagnetic iron oxide nanoparticles (SPION)/polymeric nanocomposite for magnetic resonance imaging (MRI) and drug delivery, manganese-doped zinc sulfide (Mn:ZnS) quantum dots (QDs)/ SPION/ polymeric nanocomposites for fluorescence imaging, MRI and drug delivery. LÄS MER
20. Compact Soft X-Ray Microscopy : Sources, Optics and Instrumentation
Sammanfattning : This thesis describes the development of a sub-60-nm full-period resolution compact soft x-ray microscope operating in the water-window region (2.3-4.4 nm). Soft x-ray water-window microscopy is a powerful technique for high-resolution imaging of organic materials exploiting the natural contrast mechanism between carbon and oxygen, cf. LÄS MER