Sökning: "Biokemi och molekylärbiologi"

Visar resultat 21 - 25 av 1399 avhandlingar innehållade orden Biokemi och molekylärbiologi.

  1. 21. Proteomics as a multifaceted tool in medicine and environmental assessment

    Författare :Jacob Kuruvilla; Susana Cristobal; Mats Lindahl; Mikael Sigvardsson; Jean Armengaud; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Proteomics is evolving as a multi-faceted tool for addressing various biochemical and biomedical queries in the field of scientific research. This involves various stages, ranging from sample preparation to data analysis and biological interpretation. LÄS MER

  3. 22. Resistance to neuraminidase inhibitors in influenza A virus isolated from mallards

    Författare :Goran Orozovic; Björn Olsen; Johan Lennerstrand; Sigvard Olofsson; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; influenza; mallards; neuraminidase; PCR; sequencing; mutation; oseltamivir; zanamivir; resistance; NAI; antivirals; pandemic; Virology; Virologi; Molecular biology; Molekylärbiologi; Bioinformatics; Bioinformatik; Zoonotisk ekologi; Zoonotic Ecology; Virology; Virologi; Biokemi; Biochemistry;

    Sammanfattning : Influenza A virus belongs to the Orothomyxoviridae family of viruses and is one of the most common pathogens that cause infections of the respiratory tract. The aim of this thesis was to investigate if neuraminidase inhibitor (NAI) Tamiflu® (oseltamivir, OC) and Relenza® (zanamivir, ZA) - related resistance mutations exist in the neuraminidase (NA) gene of viruses collected from wild birds. LÄS MER

  4. 23. Molecular Regulation of Inflammation and Angiogenesis in the Tumor Microenvironment

    Författare :Lothar Dieterich; Anna Dimberg; Lena Claesson-Welsh; Jonas Fuxe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; stroma; glioma; alphaB-crystallin; HSPB5; cryab; myeloid cells; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Tumor growth and progression not only depend on properties of the malignant cells but are strongly influenced by the tumor microenvironment. The tumor stroma consists of various cell types such as inflammatory cells, endothelial cells and fibroblasts, which can either inhibit or promote tumor growth. LÄS MER

  5. 24. Articular cartilage proteoglycan biosynthesis and sulfation

    Författare :Chengjuan Qu; Mikko Lammi; Heikki Helminen; Juha Töyräs; Anna-Marja Säämänen; Finland Kuopio University of Kuopio Anatomy Department of Biomedicine; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cartilage; Chondrocytes metabolism; Chondroitin sulfates; Glycosaminoglycans; Osteoarthritis; Proteoglycans; Glucosamine; Sulfation; Biochemistry; biokemi; cellforskning; cell research; Orthopaedics; ortopedi;

    Sammanfattning : Glucosamine (GlcN) and glucosamine sulfate (GS) have been used to treat the patients with osteoarthritis(OA) as a disease-modifying agent. Previousin vitro studies have focused on the effects of GlcN or GSon cartilage metabolism, whereas in vivo studies have investigated their potential for the treatment of OA. LÄS MER

  7. 25. The receptor tyrosine kinase Met and the protein tyrosine phosphatase PTPN2 in breast cancer

    Författare :Cynthia Veenstra; Olle Stål; Gizeh Perez-Tenorio; Pietras Kristian; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Breast cancer is the most common form of cancer in women worldwide and the second leading cause of cancer death. It is a heterogeneous disease and is subdivided into different subtypes, all with different treatment responses and survival outcomes. LÄS MER