Sökning: "Biofysik"
Visar resultat 21 - 25 av 683 avhandlingar innehållade ordet Biofysik.
21. New approaches to data-driven analysis and enhanced sampling simulations of G protein-coupled receptors
Sammanfattning : Proteins are large biomolecules that carry out specific functions within living organisms. Understanding how proteins function is a massive scientific challenge with a wide area of applications. In particular, by controlling protein function we may develop therapies for many diseases. LÄS MER
22. High-resolution Imaging of Cleared and Expanded Kidney Tissue Samples
Sammanfattning : The kidney is one of the most important and complex organs in the humanbody with the task of filtering hundreds of litres of blood daily. It is responsiblefor the salt and acid/base balance in the body, as well as secretinghormones important for red blood cell production and blood pressure regulation. LÄS MER
23. Studies on the Role of Apoptosis in Kidney Diseases
Sammanfattning : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. LÄS MER
24. Characterization of membrane protein active transport under native-like conditions
Sammanfattning : P-type ATPase proteins are a family of membrane proteins that maintain concentration gradients of e.g. ions by ATP-driven transport across the membrane. While these transporters share many features in their molecular architecture, structural differences are required to convey ion specificity. LÄS MER
25. Computational Study of Calmodulin’s Ca2+-dependent Conformational Ensembles
Sammanfattning : Ca2+ and calmodulin play important roles in many physiologically crucial pathways. The conformational landscape of calmodulin is intriguing. Conformational changes allow for binding target-proteins, while binding Ca2+ yields population shifts within the landscape. Thus, target-proteins become Ca2+-sensitive upon calmodulin binding. LÄS MER