Sökning: "Biofunctionality"

Hittade 4 avhandlingar innehållade ordet Biofunctionality.

1. 1. Modular Hyaluronan-Based Hydrogels for 3D Cell Culture and Bioprinting

   Författare :Michael Jury; Daniel Aili; Robert Selegård; My Hedhammar; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; 3D cell-culture; Biofunctionality; Bioprinting;

   Sammanfattning : Three-dimensional (3D) cell culture facilitates development of biological relevant assays for drug screening and toxicity testing. Compared to conventional 2D cell culture, cells cultured in 3D can more accurately mimic human tissues and organs and thus provide ex vivo data with potentially better predictive value for cancer research, pharmacology, and toxicology, reducing the need for animal models, improving experimental reproducibility, and reducing time and costs in drug development. LÄS MER

3. 2. Functional polymer brush coatings for nanoscale devices

   Författare :John Andersson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; poly ethylene glycol ; nanopores; electrochemistry; silatranes; func- tional materials; polymer brush; Nanobiotechnology; interpolymer complex; pH re- sponsive; macromolecular gating.;

   Sammanfattning : Nanobiotechnology is an interdisciplinary field that has garnered considerable attention for offering exciting new opportunities of studying and manipulating biomolecules at the nanoscale. This prospect bears large potential benefits in the field of medicine and the whole life science sector in general. LÄS MER

4. 3. QCM-D – with focus on biosensing in biomolecular and cellular systems

   Författare :Erik Nilebäck; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; biomolecular interactions; cell-surface interaction; glycosaminoglycans; viscoelasticity; cell morphology; Quartz crystal microbalance with dissipation monitoring; surface chemistry; protein conformation;

   Sammanfattning : The high degree of complexity in biological systems is being investigated in greater and greater detail by increasingly sophisticated sensing approaches. The quartz crystal microbalance with dissipation monitoring (QCM-D) technique stands out in this context, by probing the viscoelastic properties at interfaces. LÄS MER

5. 4. Spider Silk Nanostructuring and its Applications for Tissue Engineering

   Författare :Linnea Gustafsson; Wouter van der Wijngaart; David Kaplan; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; recombinant spider silk; nanostructures; microstrucutres; nanowires; nanochains; nanodisks; nanomembranes; tissue engineering; in-vitro models; medical technology; health technology; nanomedicine; rekombinant spindelsilke; nanostrukturer; mikrostrukturer; nanotrådar; nanokedjor; nanodiskar; nanomembran; vävnadsteknik; in vitro-modeller; medicinsk teknik; hälsoteknik; nanomedicin; Electrical Engineering; Elektro- och systemteknik;

   Sammanfattning : This thesis introduces new ways to produce micro-and nanostructures of recombinant spider silk and explores ways to characterize their topography, mechanical properties, cell compatibility, and permeability. The suitability of the formed structures for applications within tissue engineering, primarily in vitro tissue modeling, is also investigated. LÄS MER