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  1. 1. Biodegradable Thermoplastic Elastomers

    Författare :Basse Asplund; Jöns Hilborn; Tim Bowden; Iskender Yilgör; Uppsala universitet; []
    Nyckelord :Chemistry; poly urethane ; poly urethane urea ; biomaterial; biodegradable; polymer; thermoplastic elastomer; haemocomatible; tissue engineering; biocompatible; Kemi;

    Sammanfattning : A novel strategy for synthesising segmented poly(urethane urea) (PUU) without using a chain extender but nevertheless with the opportunity to vary the hard segment content has been developed. The strategy is based on amine formation from isocyanate upon reaction with water. LÄS MER

  2. 2. Synthesis, Characterisation and Properties of Biomimetic Biodegradable Polymers

    Författare :Fredrik Nederberg; Tim Bowden; Nicola Tirelli; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; biodegradable polymers; biomimetic; phospholipid-like; phosphorylcholine; amphiphilic; ionomer; hemocompatible; non-adhesive; water uptake; reduced protein adsorption; protein delivery; Kemi; Chemistry; Kemi;

    Sammanfattning : The acceptance of blood contacting implants creating favorable conditions in vivo is decisively determined by their interaction with proteins that mediate inter cellular interactions with synthetic substrates. Adsorbed proteins can activate blood cascade systems like coagulation and complement that may result in serious blood clots, and/or immunological reactions. LÄS MER

  3. 3. Cell Membrane Mimetic Biodegradable Polymers

    Författare :Fredrik Nederberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; Oorganisk kemi;

    Sammanfattning : .... LÄS MER

  4. 4. Functional Cyclic Carbonate Monomers and Polycarbonates : Synthesis and Biomaterials Applications

    Författare :Jonas Mindemark; Tim Bowden; Andrew Dove; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA condensation; gene delivery; ionomers; polyplexes; self-assembly; amphiphiles; biodegradable; biological applications of polymers; transfection; cyclic carbonate monomers; polycarbonates; semicrystalline polymers; click chemistry; triazoles; cycloaddition; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Sammanfattning : The present work describes a selection of strategies for the synthesis of functional aliphatic polycarbonates. Using an end-group functionalization strategy, a series of DNA-binding cationic poly(trimethylene carbonate)s was synthesized for application as vectors for non-viral gene delivery. LÄS MER

  5. 5. Strategies for building polymers from renewable sources : Using prepolymers from steam treatment of wood and monomers from fermentation of agricultural products

    Författare :Margaretha Söderqvist Lindblad; KTH; []
    Nyckelord :renewable sources; biodegradable polymers; hemicellulose; 2-hydroxyethyl methacrylate; modification of hemicellulose; methacrylation reaction; rheology measurements; dynamic-mechanical behavior; 1; 3-propanediol; 1; 4-cyclohexanedimethanol; succinic ac;

    Sammanfattning : A strategic research area today is development of polymericproducts made from renewable sources. The ways of utilizingrenewable sources studied in this thesis are using 1)prepolymers obtained by steam treatment of wood and 2) monomersobtainable by fermentation of agricultural products. LÄS MER