Sökning: "Bio-distribution"

Hittade 2 avhandlingar innehållade ordet Bio-distribution.

  1. 1. Degradation, Metabolism and Relaxation Properties of Iron Oxide Particles for Magnetic Resonance Imaging

    Författare :Karen Briley Saebo; Håkan Ahlström; Atle Bjørnerud; Michael Knopp; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic Resonance Imaging; contrast agents; iron oxide particles; metabolism; relaxation mechanisms; Radiologisk forskning; Radiological research; Radiologisk forskning;

    Sammanfattning : Whereas the effect of size and coating material on the pharmacokinetics and biodistribution of iron oxide based contrast agents are well documented, the effect of these parameters on liver metabolism has never been investigated. The primary purpose of this work was to evaluate the effect of iron oxide particle size and coating on the rate of liver clearance and particle degradation using a rat model. LÄS MER

  2. 2. Human amnion epithelial stem cells as a therapy for liver disease

    Författare :Raghuraman Chittoor Srinivasan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Placenta-derived stem cells have been proposed as potential new treatments for acute and congenital liver diseases. Of all the different perinatal tissues, amnion membrane and isolated amnion epithelial cells have been shown to be an outstanding readily available source of multipotent stem cells. LÄS MER