Sökning: "Bingnan Li"

Hittade 1 avhandling innehållade orden Bingnan Li.

  1. 1. Telomerase in hematological and other malignancies : therapeutic implications

    Författare :Bingnan Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The Telomere is a nucleoprotein complex consisting of TTAGGG repeated sequences covered by specialized binding proteins termed shelterins masking the end of linear chromosomes and thereby protecting the end of the chromosome from genomic instability. Telomeres become progressively shortened during cellular replication and acts as a mitotic clock to confer a limited lifespan to normal cells. LÄS MER