Sökning: "Binding kinetics"

Visar resultat 1 - 5 av 232 avhandlingar innehållade orden Binding kinetics.

1. 1. Binding Kinetics of Proteins at Immune-Cell Contacts

   Författare :Manto Chouliara; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T cells; Binding Kinetics; Affinity; Lifetime; CD4; CD2; TIRF Microscopy; SLBs;

   Sammanfattning : Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. It is therefore not surprising that these interactions also govern the response of our body´s defence mechanism, the so-called immune system, towards an infection. LÄS MER

3. 2. Evolution and Binding Mechanisms of Intrinsically Disordered Proteins

   Författare :Elin Karlsson; Per Jemth; Kaare Teilum; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intrinsically disordered proteins; Protein evolution; Binding kinetics; Binding mechanisms; Biophysical characterisation; Medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : Intrinsically disordered proteins (IDPs) make up a considerable fraction of the proteome in eukaryotic organisms. These proteins often act as hubs in interaction networks, harbouring multiple interaction with other proteins, and thus evolution has to walk a tightrope to accommodate new interactions while maintaining the previously established interactions. LÄS MER

4. 3. Structural and Functional Studies of Wilms Tumour Protein - WT1; Novel Insights into Functionality of Zinc Finger Proteins

   Författare :Elmar Nurmemmedov; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; function; structure; transcription factor; cancer; affinity; kinetics; Biacore; RNA binding; DNA binding; Wilms tumour WT1 ; zinc finger;

   Sammanfattning : The molecular process under which message in DNA is relayed onto RNA is called transcription, and it accomplished through involvement of so-called transcription factors. Zinc finger proteins are one of the most abundant classes of regulatory proteins in eukaryotic cells where they play central roles in a variety of cellular activities. LÄS MER

5. 4. On semirigid binuclear ruthenium complexes and DNA : binding modes and kinetics

   Författare :Fredrik Westerlund; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; binding kinetics; polarized light spectroscopy; threading; intercalation; SDS-sequestered dissociation; FRET; DNA; ruthenium complexes;

   Sammanfattning : .... LÄS MER

7. 5. The kinetics of cellulose enzymatic hydrolysis : Implications of the synergism between enzymes

   Författare :Priit Väljamäe; Jan-Christer Janson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Acetobacter; Cellobiohydrolase; Cellobiose; Cellulase; Cellulose; Diffusion; Endoglucanase; Hydrolysis; Inhibition; Kinetics; Model; Product; Substrate; Surface; Synergism; Trichoderma reesei; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : The hydrolysis kinetics of bacterial cellulose and its derivatives by Trichoderma reesei cellulases was studied. The cellulose surface erosion model was introduced to explain the gradual and strong retardation of the rate of enzymatic hydrolysis of cellulose. LÄS MER