Sökning: "Bethany"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet Bethany.

  1. 1. Folate in cancer and cardiovascular disease : prospective studies from the population-based northern Sweden health and disease study

    Författare :Bethany van Guelpen; Åke Bruce; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : BACKGROUND: Folate, a B-vitamin found primarily in fruits and vegetables, especially leafy greens, and other B-vitamins involved in folate metabolism are believed to protect against cancer and cardiovascular disease. Maintaining an adequate folate status ensures availability of methyl groups for DNA synthesis and for all methylation reactions in the body, and prevents the accumulation of homocysteine, a sulphur-containing amino acid that has been linked to cardiovascular disease. LÄS MER

  3. 2. Inflammation and risk of chronic diseases with a focus on colorectal cancer and the impact of dietary patterns

    Författare :Stina Bodén; Bethany van Guelpen; Sophia Harlid; Maria Wennberg; Lena Maria Nilsson; Katarina Bälter; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nutritional epidemiology; dietary patterns; epidemiology; cancer; colorectal cancer; chronic low-grade inflammation; biomarkers; metabolomics; nutritionsepidemiologi; kostmönster; epidemiologi; cancer; kolorektalcancer; kronisk låggradig inflammation; biomarkörer; metabolomik; epidemiologi; Epidemiology;

    Sammanfattning : .... LÄS MER

  4. 3. The CpG island methylator phenotype in colorectal cancer : studies on risk and prognosis

    Författare :Anna Dahlin; Richard Palmqvist; Bethany van Guelpen; Maria Henriksson; Åke Öberg; Xiao-Feng Sun; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; DNA methylation; folate; microsatellite instability MSI ; prognosis; risk factors; t-lymphocytes; the CpG island methylator phenotype CIMP ; Vitamin B12; Pathology; Patologi; Tumour biology; Tumörbiologi; patologi; Pathology;

    Sammanfattning : Background Colorectal cancer (CRC) is the second most common malignancy in developed countries. The mortality is high, with nearly half of patients dying from the disease. The primary treatment of CRC is surgery, and decisions about additional treatment with chemotherapy are based mainly on tumor stage. LÄS MER

  5. 4. Circulating markers of risk and etiology in colorectal cancer

    Författare :Justin Harbs; Sophia Harlid; Bethany van Guelpen; Xijia Liu; Henrik Grönberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; CRC; sex hormones; colon cancer; DNA methylation; proteomics; risk; etiology; Cancer Epidemiology; cancerepidemiologi;

    Sammanfattning : Background: Colorectal cancer is the third most commonly diagnosed cancer in men and women. Worldwide around 2 million individuals are diagnosed each year – a number expected to increase as colorectal cancer risk factors become more prevalent. LÄS MER

  7. 5. Antibiotics use in relation to colorectal cancer risk, survival and postoperative complications

    Författare :Sai San Moon Lu; Bethany van Guelpen; Sophia Harlid; Jonas Ludvigsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; antibiotics; gut microbiome; dysbiosis; cancer-specific survival; surgical site infections; anastomotic leakage; register-based epidemiology; Cancer Epidemiology; cancerepidemiologi; Cancer Epidemiology; cancerepidemiologi; Oncology; onkologi; Surgery; kirurgi;

    Sammanfattning : Background: Growing evidence suggests that antibiotic-induced dysbiosis of gut microbiota potentially contributes to colorectal cancer development and oncological outcomes. However, the role of antibiotics in colorectal cancer incidence, survival and postoperative outcomes at a population level remains incompletely understood. LÄS MER