Sökning: "Berolla Sahdo"

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1. 1. Inflammasomes : defense guardians in host-microbe defence

   Författare :Berolla Sahdo; Eva Särndahl; Bo Söderquist; Anna Norrby Teglund; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate immunity; inflammasome; leukocytes; cytokines; Staphylococcus aureus; Propionibacterium acnes; inflammation; infection; gene variants; polymorphism.; Biomedicin; Biomedicine;

   Sammanfattning : The inflammasomes are emerging as key regulators of the innate immune response as they response to cellular infection, tissue damage and/or stress. Activated inflammasomes provide a signalling platform for caspase-1 activation which subsequently processes the maturation of interleukin (IL)-1β and IL-18, and in addition promotes cell death, named pyroptosis. LÄS MER