Sökning: "Beroendelära"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet Beroendelära.

1. 1. Use and misuse of sedative drugs and related substances - Findings in the general population and in individuals with opioid dependence

   Författare :Tove Abrahamsson; Lund Psykiatri; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Substance use; Sedatives; Anxiolytics; Hypnotics; Prescription drug miuse; Benzodiazepines; Z-drugs; Pregabalin; Self-assessed health; Quality of life; Opioid dependence; Opiate maintenance treatment; Mortality;

   Sammanfattning : Background: Prescription sedatives are efficient in the treatment of anxiety and sleeping disorders, but are associated with a risk of misuse and dependence, as well as an increased risk of accidents, injuries and overdoses, both in the general population and especially in individuals with other substance misuse. The present thesis aims to investigate prescription sedative use and misuse in two kinds of samples - in the general population, with focus on its association with subjective health and quality life, and in the subpopulation of individuals with opioid dependence, with focus on treatment outcome in opioid maintenance treatment and mortality. LÄS MER

3. 2. Neuropeptide Receptors as Treatment Targets in Alcohol Use Disorders

   Författare :Abdul Maruf Asif Aziz; Annika Thorsell; David Engblom; Elizabeth Jerlhag; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Alcohol use disorder (AUD) is a complex disorder with multiple pathophysiological processes contributing to the initiation, progression and development of the disease state. AUD is a chronic relapsing disease with escalation of alcohol-intake over time in repeated cycles of tolerance, abstinence and relapse and hence, it is very difficult to treat. LÄS MER

4. 3. Renal and parathyroid function in psychiatric patients on lithium treatment

   Författare :Hans Bendz; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes insipidus; glomerular filtration rate; hypercalcemia; hyperparathyroidism; lithium; nephrogenic; nephropathy; polyuria;

   Sammanfattning : Aims. To investigate the prevalence and clinical implications of renal and parathyroid morbidity in lithium patients. Patients. Short-term lithium patients (n=162; average 6 treatment years) and long-term patients (n=142; average 19 treatment years) were studied cross-sectionally. LÄS MER

5. 4. Substance use in adolescents and young adults: Interactions of drugs of abuse and the role of parents and peers in early onset of substance use

   Författare :Jonas Berge; Lund Psykiatri; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Substance use; Alcohol; Tobacco; Cannabis; Illicit drugs; Adolescents; Young adults;

   Sammanfattning : Background: Misuse of substances is a major contributor to disability and mortality worldwide. The use of tobacco, alcohol, and illegal drugs in adolescence and young adulthood are well-known risk factors for subsequent substance-related harms. LÄS MER

7. 5. Brain glycine receptors as a common target for alcohol and the relapse-preventing drug acamprosate - a preclinical study

   Författare :Pei Pei Chau; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcoholism; Acamprosate; Glycine receptor; Preclinical study; Dopamine; Ethanol;

   Sammanfattning : Alcohol abuse and dependence make up the most prevalent categories of substance use disorders in the world. Converging evidence from the current research group has identified two receptor populations, the glycine (GlyRs) and nicotinic acetylcholine receptors (nAChRs) in the mesolimbic dopamine system, as two potentially important targets for the development of new medication to treat alcohol dependence. LÄS MER