Sökning: "Bernd Meibohm"

Hittade 1 avhandling innehållade orden Bernd Meibohm.

1. 1. Pharmacokinetic-Pharmacodynamic Evaluations and Experimental Design Recommendations for Preclinical Studies of Anti-tuberculosis Drugs

   Författare :Chunli Chen; Ulrika Simonsson; Mats Karlsson; Sebastian Wicha; Bernd Meibohm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculosis; pharmacokinetics; pharmacodynamics; pharmacometrics; the Multistate Tuberculosis Pharmacometric model; the General Pharmacodynamic Interaction model; optimized design; rifampicin; isoniazid; ethambutol; pyrazinamide; Pharmaceutical Science; Farmaceutisk vetenskap;

   Sammanfattning : Tuberculosis is an ancient infectious disease and a leading cause of death globally. Preclinical research is important for defining drugs and regimens which should be carried forward to human studies. LÄS MER