Sökning: "Bernat Crosas"

Hittade 1 avhandling innehållade orden Bernat Crosas.

1. 1. The Path to Destruction : Understanding the mechanism and regulation of proteasomal degradation

   Författare :Anne Beskow; Patrick Young; Ylva Engström; Bernat Crosas; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteasome; ubiquitin; p97; Cnc-C; transcription factors; Nrf1; Nrf2; Molecular Biology; molekylärbiologi;

   Sammanfattning : A majority of intracellular proteins are degraded by the ubiquitin proteasome system (UPS). In this thesis, both the mechanism of the degradation and the regulation of UPS have been investigated. The importance of the p97 ATPase for proteasomal degradation of cytosolic substrates was examined. LÄS MER