Sökning: "Bergrún Tinna Magnúsdóttir"

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  1. 1. Estimation and optimal designs for multi-response Emax models

    Författare :Bergrún Tinna Magnúsdóttir; Hans Nyquist; Ziad Taib; Nancy Flournoy; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; multi-response Emax models; Clinical Utility Index CUI ; optimal designs; system estimation; dose-response studies.; Statistics; statistik;

    Sammanfattning : This thesis concerns optimal designs and estimation approaches for a class of nonlinear dose response models, namely multi-response Emax models. These models describe the relationship between the dose of a drug and two or more efficacy and/or safety variables. LÄS MER