Sökning: "Benzodiazepiner"

Hittade 3 avhandlingar innehållade ordet Benzodiazepiner.

  1. 1. Pharmacophore Refinement and Lead Optimization - A study of the benzodiazepine site of the GABAA receptors

    Författare :Erik Lager; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; Naturvetenskap; Natural science; Quinolone; Flavone; Pharmacophore; GABA; Benzodiazepine;

    Sammanfattning : Structure activity relationship studies of synthetic flavone derivatives have been utilized to refine and evaluate a pharmacophore model of the benzodiazepine binding site of the GABAA receptors, originally developed by Zhang et al. (Drug Des. Discovery 1995, 12, 193-248). LÄS MER

  3. 2. Migration and Mental Health: Epidemiological Studies of Immigrants in Sweden

    Författare :Louise Bayard-Burfield; Samhällsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; suicide attempt; self-reported psychiatric illnes; psychotropic drugs; Ethnicity; mortality; Social medicine; Socialmedicin; samhällsmedicin;

    Sammanfattning : Abstract Aims: To analyse the influence of migration status (country of birth/ethnicity), accultura-tion, socio-economic and psychosocial factors on self-reported psychiatric illness, suicide attempt, total mortality and violent death. Methods: Three main data sources were used: suicide attempts in the catchment area of Lund University Hospital (PASIS) during 1991–94; the Swedish Survey of Living Conditions (ULF) 1979–1985 (n=39,155) and 1986–93 (n=36,890); the Swedish National Survey of Immigrants (born in Iran, Chile, Turkey, Kurdistan or Poland) from 1996 (n=1,980). LÄS MER

  4. 3. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain

    Författare :Catarina Lindquist; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; Ion channels; GABA; Inhibition;

    Sammanfattning : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). LÄS MER