Sökning: "Behrous Davani"

Hittade 1 avhandling innehållade orden Behrous Davani.

1. 1. Increased glucocorticoid sensitivity in pancreatic beta-cells : effects on glucose metabolism and insulin release

   Författare :Behrous Davani; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Glucocorticoids; glucocorticoid receptor; Pancreatic beta-cell; Type 2 diabetes; insulin release;

   Sammanfattning : Type 2 diabetes mellitus (T2DM) is characterized by three pathological alterations: (1) insulin resistance in peripheral tissues, (2) increased hepatic glucose production and (3) impaired insulin secretion from the pancreatic beta-cells. Glucocorticoids (GCs) exert profound effects on glucose homeostasis. LÄS MER