Sökning: "Bcl-2"

Visar resultat 16 - 20 av 135 avhandlingar innehållade ordet Bcl-2.

  1. 16. Prognostic Factors in Early Stages (FIGO I-II) of Epithelial Ovarian Carcinoma

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ingirídur Skírnisdóttir; Uppsala universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Ovarian cancer; early stages; adjuvant therapy; prognosis; tumor grade; apoptotic regulators; p53; bcl-2; bax; growth factor receptors; HER-2 neu; EGFR; DNA ploidy; Obstetrik och kvinnosjukdomar; MEDICINE Surgery Obstetrics and women s diseases; MEDICIN Kirurgi Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

    Sammanfattning : From January, 1988, to December, 1993, 113 patients with FIGO stage IA-IIC epithelial ovarian carcinoma were treated with postoperative radiotherapy. The median follow-up period was 74 months. Tumor recurrences were recorded in 33 cases (30%). The cancer-specific survival rate was 72%. LÄS MER

  3. 17. Fetal Outcome in Experimental Diabetic Pregnancy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sheller Zabihi; Uppsala universitet.; [2008]
    Nyckelord :Cell biology; Rat; Mouse; TG; KO; Diabetes in Pregnancy; Embryo; Folic acid; Superoxide dismutase; Catalase; Glutathione peroxidase; Vascular endothelial growth factor-A; Folate binding protein-1; Bax; Bcl-2; Caspase-3; P53; Pax-3; Blood flow; Cellbiologi;

    Sammanfattning : Women with pregestational diabetes have a 2-5 fold increased risk of giving birth to malformed babies compared with non-diabetic women. Diabetes-induced oxidative stress in maternal and embryonic tissues has been implicated in the teratogenic process. LÄS MER

  4. 18. Molecular Studies of Mast Cell Migration and Apoptosis Two Ways of Regulating Mast Cell Numbers at Sites of Inflammation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jessica Alfredsson; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; SCF; IL-3; FcεRI; migration; apoptosis; Bim; Bcl-2; Bcl-XL; Akt; FOXO; MAPK; Patologi; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi;

    Sammanfattning : Upon activation mast cells release numerous proinflammatory mediators. With this feature, mast cells play an important role in host defense against pathogens, and are involved in tissue remodeling and wound healing. However, in cases of excessive inflammation the effects of mast cells are detrimental. LÄS MER

  5. 19. Markers predicting sensitivity to polyamine depletion in human breast cancer cell lines

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Veronica Johansson; Lunds universitet.; Lund University.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PCNA; PAO; human breast cancer cell lines; FEN1; DNA strand breaks; DNA ligase I; apoptosis; Bcl-2; polyamine analogues; pRb;

    Sammanfattning : In spite of different treatment strategies today, breast cancer mortality is still high and new treatments are therefore needed. Potential new treatments can be found among the polyamine analogues. Polyamine analogues can be used in cancer treatment as cancer cells have a higher requirement for polyamines than the surrounding healthy tissue. LÄS MER

  7. 20. Prognosis in carcinoma in situ of the breast

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Fredrik Wärnberg; Uppsala universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Breast carcinoma; ductal carcinoma in situ; lobular carcinoma in situ; prognosis; histopathological grade; p53; c-erbB-2; Ki 67; Bcl-2; hormone receptors; angiogenesis; Kirurgi; MEDICINE Surgery; MEDICIN Kirurgi; Surgery; kirurgi;

    Sammanfattning : The incidence of breast cancer is rising steadily in Sweden and the proportion of carcinoma in situ (CIS) has increased appreciably, most likely due to mammography screening. The aim of this study was twofold: (1) to examine risk factors for subsequent invasive breast carcinoma and breast cancer death after primary ductal carcinoma in situ (DCIS) and (2) to study the biology in the progress between in situ and invasive carcinoma. LÄS MER