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Visar resultat 1 - 5 av 106 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Context dependent adaptation of biting behavior in human

    Författare :Anders Johansson; Benoni Edin; Karl-Gunnar Westberg; Peter Svensson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EMG; bite force; human; mastication; muscles; jaw opening reflex; motor control; reflex modulation; periodontal attachment loss; periodontitis; fysiologi; Physiology;

    Sammanfattning : The focus of this thesis was to study an action that humans perform regularly, namely, to hold a morsel between the teeth and split it into smaller pieces. Three different issues related to this biting behavior were addressed:  (1) the effect of redu­c­ed perio­dontal tissues on food holding and splitting behavior; (2) the behavioral conse­quences of performing different bite tasks with different functional requirements, i. LÄS MER

  3. 2. Proteomics informed investigation of human hepatocytes and liver tissue

    Författare :Niklas Handin; Per Artursson; Peter Nygren; Tobias Sjöblom; Mårten Fryknäs; Pieter Annaert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; liver; hepatocytes; proteomics; cellular stress; apoptosis; hepatotoxicity; 3D culture; spheroid; drug metabolism; drug toxicity; drug transport; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : A successful drug needs to display beneficial absorption, distribution, metabolism, excretion and toxicity (ADME-Tox) profile. It is therefore important to investigate these properties during the drug discovery process. LÄS MER

  4. 3. Human papillomavirus and cellular biomarkers in cervical cancer

    Författare :Malin Kaliff; Gabriella Lillsunde-Larsson; Mats G. Karlsson; Tina Dalianis; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; HPV; screening; triage; prognosis; genotype distribution; multiple HPV; HPV-negative; viral load; methylation;

    Sammanfattning : Cervical cancer (CC) is caused by a persistent infection of certain types of the human papillomavirus (HPV). Even though great progress has been made in strategies for prevention, and treatment of CC, there is still a need for improved methods in screening and management of women diagnosed with CC. LÄS MER

  5. 4. Designing a digital pathology workstation for routine practice

    Författare :Jesper Molin; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Human-computer interaction; Navigation; Digital pathology;

    Sammanfattning : The role of the pathology lab is important in the future of cancer care. In orderto further personalize the care for cancer patients, more precise review of tumorspecimens is needed in order to guide clinicians between different treatmentstrategies. LÄS MER

  7. 5. Building muscle : a translation of training adaptation

    Författare :Niklas Boman; Michael Svensson; Jonas Burén; Henrik Antti; Eva Jansson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Training; adaptation; muscle; human; hypertrophy; testosterone; fysiologi; Physiology;

    Sammanfattning : Training is preparation for what is expected to come through utilization of the plastic and resistive features of nature, known as adaptation. As such, training in humans may have a number of desired goals. These are typically related to sports performance or education. Whatever the goal, a plan needs to be made for reaching it. LÄS MER