Sökning: "Bartek Zuber"

Hittade 1 avhandling innehållade orden Bartek Zuber.

1. 1. Targeting HIV-1 entry and reverse transcription by vaccination

   Författare :Bartek Zuber; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HIV-1; DNA vaccination; coreceptor; CCR5; RT; drug resistance; CpG; pseudovirus;

   Sammanfattning : Human immunodeficiency virus type I (HIV-1) is a complex retrovirus, which uses the CD4 receptor and chemokine receptors to infect its target cells. The chemokine receptor CCR5 is essential for primary HIV-1 infection. The hallmark of retroviruses is the enzyme reverse transcriptase (RT), which transcribes the virus genome from RNA to DNA. LÄS MER