Sökning: "BabA adhesin"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden BabA adhesin.

  1. 1. Helicobacter pylori adhesion and patho-adaptation : the role of BabA and SabA adhesins in persistent infection and chronic inflammation

    Författare :Jafar Mahdavi; Henrik Clausen; Umeå universitet; []
    Nyckelord :H. pylori; BabA; adhesin; Lewis b; MUC5AC; sialyl-dimeric-Lewis x; chronic inflammation; SabA; Lewis x; LPS; odontologi; Odontology;

    Sammanfattning : Helicobacter pylori (H. pylori) is a human-specific gastric pathogen which is responsible for a spectrum of diseases ranging from superficial gastritis to gastric and duodenal ulceration, and which is also highly associated with gastric cancer. The pathogenesis of severe gastric disorders caused by H. LÄS MER

  3. 2. Adaptation of Helicobacter pylori Adherence Properties in Promotion of Host Tropism and Inflammatory Disease

    Författare :Marina Aspholm; Rino Rappuoli; Umeå universitet; []
    Nyckelord :H. pylori; BabA; SabA; adhesin; blood group antigens; sialylated; phase variation; hemagglutination; selectin; adaptation; odontologi; Odontology;

    Sammanfattning : Being among the most prevalent of persistent infectious agents in humans worldwide, Helicobacter pylori induces chronic inflammation (gastritis), which may progress to peptic ulceration and stomach cancer. The ability to adhere to the gastric mucosa is considered to be both a colonization and virulence property of H. pylori. For adherence, H. LÄS MER

  4. 3. Helicobacter pylori : molecular mechanisms for variable adherence properties

    Författare :Anna Vallström; Anna Arnqvist; Kristian Riesbeck; Umeå universitet; []
    Nyckelord :H. pylori; adherence; BabA; SabA; Leb; sLex; phase variation; recombination; vesicles;

    Sammanfattning : More than half of all people worldwide are infected with H. pylori. The infection always cause a gastric inflammation that may develop into peptic ulcer disease or gastric cancer. Attachment proteins, adhesins, mediate specific adherence of H. LÄS MER

  5. 4. Helicobacter spp. interactions with mucins: adhesion and mucin regulation of pathogen proliferation and gene expression

    Författare :Emma C Skoog; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter; mucin; glycosylation; Lactobacillus; adhesion; proliferation; gene expression; CagA; SabA; BabA; ArsS; Fur;

    Sammanfattning : Helicobacter pylori colonizes the gastric mucosa of approximately half of the world’s population and is a risk factor for gastritis, peptic ulcers and gastric cancer. H. pylori is surrounded by, and adheres to, the heavily glycosylated mucins that build up the mucus layer. The carbohydrate structures on the mucins that act as ligands for H. LÄS MER

  7. 5. Diversity and adaptation in the adherence properties of Helicobacter pylori

    Författare :Melissa Méndez; Thomas Borén; Samuel Lundin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; transmission; phylogeny; native populations; bacterial adherence; BabA adhesin; receptor specificity; functional polymorphism; genetic diversity; adaptation;

    Sammanfattning : .... LÄS MER