Sökning: "BMP"

Visar resultat 16 - 20 av 93 avhandlingar innehållade ordet BMP.

  1. 16. Molecular regulators in cartilage and bone formation

    Författare :Thomas Engstrand; Uppsala universitet; []
    Nyckelord :Medical sciences; cartilage; bone; TGF-beta; BMP; noggin; gene therapy; gene targeting; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Cartilage functions as a scaffold for bone formation during development. This process, endochondral ossification, is regulated by systemic hormones and local growth factors. LÄS MER

  3. 17. Molecular heterogeneity of prostate cancer bone metastasis

    Författare :Erik Bovinder Ylitalo; Pernilla Wikström; Anders Bergh; Maria Brattsand; Vessela Kristensen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; CRPC; castration-resistant; androgen receptor; splice variant; abiraterone; cabazitaxel; ABCB1; cholesterol; Mdr1; P-gp; bone metastasis; immune response; metabolism; osteoblast; osteoclast; BMP; methylation;

    Sammanfattning : Castration-resistant prostate cancer (CRPC) develops after androgen deprivation therapy of advanced PC, often with metastatic growth in bone. Patients with metastatic CRPC have very poor prognosis. Growth of CRPC, in most but not all patients, seems to involve androgen receptor (AR) activity, despite castrate levels of serum testosterone. LÄS MER

  4. 18. Reducing Stormwater Pollution - Performance of Retention Ponds and Street Sweeping

    Författare :Jonas German; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; urban runoff; street sweeping; removal processes; treatment; removal efficiency; sediment; stormwater; BMP; modelling; pond;

    Sammanfattning : Stormwater, in this study defined as surface runoff in urban areas, is known to transport large quantities of toxic substances to receiving waters. Therefore different practices to treat stormwater have been proposed. In Sweden retention ponds have become a common treatment method during the past decade. LÄS MER

  5. 19. BMP - a key signaling molecule in specification and morphogenesis of sensory structures

    Författare :Vijay Kumar Jidigam; Lena Gunhaga; Jonas von Hofsten; Richard A. Lang; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; BMP signaling; Placode morphogenesis; lens; retina; olfactory; otic; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : Cranial placodes are transient thickenings of the vertebrate embryonic head ectoderm that will give rise to sensory (olfactory, lens, and otic) and non-sensory (hypophyseal) components of the peripheral nervous system (PNS). In most vertebrate embryos, these four sensory placodes undergo invagination. LÄS MER

  7. 20. Experimental Studies of BMP Signalling in Neuronal Cells

    Författare :Susanna Althini; Ted Ebendal; Carl-Henrik Heldin; Ingrid Strömberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Bone Morphogenetic Protein BMP ; Growth Differentiation Factor 10 GDF10 ; Aktivne-receptor Like Kinase 2 ALK2 ; Tyrosine Hydroxylase TH ; Neurotrophic Factor; Neurite Outgrowth; Hippocampus; Catecholamine; PC12; Sympathetic Ganglia; Substantia Nigra SN ; Gene Targeting; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; Medicinsk utvecklings- och neurobiologi;

    Sammanfattning : The developing nervous system depends largely on extracellular cues to shape its complex network of neurons. Classically, neurotrophins are known to be important mediators in this process. LÄS MER